SCHEMBL35210316

SCHEMBL35210316

C=CC(=O)Nc1cc(Nc2cc(Nc3ccc(OC)c(Cl)c3)ncn2)c(OC)cc1OCCN1CCCC1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 13/20 0.56
CYP3A4 P08684 1/20 0.49
FGFR3 P22607 1/20 0.49
KDR P35968 6/20 0.48
ERBB2 P04626 4/20 0.48
ERBB4 Q15303 4/20 0.48
ERBB3 P21860 3/20 0.48
SRC P12931 3/20 0.48
EPHB4 P54760 3/20 0.48
KIT P10721 2/20 0.48
GAK O14976 2/20 0.48
RIPK2 O43353 2/20 0.48
LCK P06239 2/20 0.48
JAK3 P52333 2/20 0.48
RIPK3 Q9Y572 2/20 0.48
AXL P30530 2/20 0.48
BMPR1B O00238 1/20 0.48
CIT O14578 1/20 0.48
MAP2K7 O14733 1/20 0.48
EPHB6 O15197 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20548915 1.00 EGFR (0.56) EGFRCYP3A4FGFR3KDRERBB2
SCHEMBL19089512 0.93 EGFR (0.56) EGFRKDRERBB2ERBB4ERBB3
SCHEMBL35210333 0.93 EGFR (0.56) EGFRKDRERBB2ERBB4ERBB3
SCHEMBL35210259 0.90 EGFR (0.56) EGFRCYP3A4FGFR3KDRFGFR1
SCHEMBL20548911 0.90 EGFR (0.56) EGFRCYP3A4FGFR3KDRFGFR1
SCHEMBL19089422 0.89 EGFR (0.55) EGFRCYP3A4FGFR3KDRFGFR1
SCHEMBL20548833 0.88 EGFR (0.58) EGFRKDRERBB2ERBB4ERBB3
SCHEMBL35210271 0.88 EGFR (0.58) EGFRKDRERBB2ERBB4ERBB3
SCHEMBL35210266 0.87 EGFR (0.66) EGFRKDRERBB2ERBB4ERBB3
SCHEMBL19089545 0.87 EGFR (0.66) EGFRKDRERBB2ERBB4ERBB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3398939-B1 ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY ANCUREALL PHARMACEUTICAL SHANGHAI CO LTD (CN) 2026-05-06 EP claimed
EP-3398939-B1 ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY ANCUREALL PHARMACEUTICAL SHANGHAI CO LTD (CN) 2026-05-06 EP disclosed