Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.56 |
| ▸ | SCN1A | P35498 | 1/20 | 0.56 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.56 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17848758 | 1.00 | DRD2 (1.00) | DRD2ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL17848530 | 1.00 | DRD2 (1.00) | DRD2ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL17848500 | 0.88 | DRD2 (1.00) | DRD2ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL35210314 | 0.88 | DRD2 (1.00) | DRD2ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL17848499 | 0.88 | DRD2 (1.00) | DRD2ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL17848715 | 0.87 | DRD2 (0.77) | DRD2ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL17848714 | 0.87 | DRD2 (0.77) | DRD2ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL17848635 | 0.86 | DRD2 (1.00) | DRD2 | |
| SCHEMBL17848637 | 0.86 | DRD2 (1.00) | DRD2 | |
| SCHEMBL17848706 | 0.86 | DRD2 (0.78) | DRD2ADRA2AADRA2BADRA2CADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233077-B1 | DOPAMINE D2 RECEPTOR LIGANDS | BROAD INST INC (US) | 2026-05-06 | — | — | EP | disclosed |