SCHEMBL35210296

SCHEMBL35210296

CC1(Oc2cccc(C(F)(F)F)c2)CCN(CCOc2ccccc2F)C1

nearest known ligand 0.79

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 15/20 0.79
LTA4H P09960 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.45
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
GAA P10253 1/20 0.44
HTT P42858 1/20 0.44
KMT2A Q03164 1/20 0.44
ABCB1 P08183 1/20 0.43
HRH3 Q9Y5N1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17848570 1.00 DRD2 (0.79) DRD2LTA4HL3MBTL1KDM4EALDH1A1
SCHEMBL17848354 0.94 DRD2 (0.70) DRD2LTA4HL3MBTL1KDM4EALDH1A1
SCHEMBL30406276 0.92 DRD2 (0.73) DRD2LTA4HL3MBTL1KDM4EALDH1A1
SCHEMBL17848552 0.92 DRD2 (0.73) DRD2LTA4HL3MBTL1KDM4EALDH1A1
SCHEMBL17848448 0.89 DRD2 (0.78) DRD2LTA4HL3MBTL1KDM4EALDH1A1
SCHEMBL17848394 0.89 DRD2 (1.00) DRD2LTA4HL3MBTL1KDM4EALDH1A1
SCHEMBL30406114 0.87 DRD2 (0.65) DRD2LTA4HL3MBTL1KDM4EALDH1A1
SCHEMBL17848391 0.87 DRD2 (0.65) DRD2LTA4HL3MBTL1KDM4EALDH1A1
SCHEMBL17848410 0.83 DRD2 (0.69) DRD2LTA4HL3MBTL1KDM4EALDH1A1
SCHEMBL17848544 0.83 DRD2 (0.69) DRD2LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3233077-B1 DOPAMINE D2 RECEPTOR LIGANDS BROAD INST INC (US) 2026-05-06 EP disclosed