SCHEMBL35210320

SCHEMBL35210320

C=CC(=O)Nc1cc(Nc2cc(Nc3ccc(F)c(Cl)c3)ncn2)c(OC)cc1OCCN(C)C

nearest known ligand 0.59

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EGFR P00533 18/20 0.59
ERBB3 P21860 1/20 0.59
DUS2 Q9NX74 1/20 0.59
KDR P35968 3/20 0.54
FGFR1 P11362 2/20 0.53
ERBB2 P04626 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19089517 1.00 EGFR (0.59) EGFRERBB3DUS2KDRFGFR1
SCHEMBL19089628 0.93 EGFR (0.55) EGFRERBB3DUS2KDRFGFR1
SCHEMBL35210345 0.93 EGFR (0.55) EGFRERBB3DUS2KDRFGFR1
SCHEMBL19089546 0.91 EGFR (0.62) EGFRERBB3DUS2KDRERBB2
SCHEMBL20548919 0.88 EGFR (0.58) EGFRERBB3DUS2
SCHEMBL35210335 0.88 EGFR (0.58) EGFRERBB3DUS2
SCHEMBL35210333 0.86 EGFR (0.56) EGFRERBB3DUS2KDRERBB2
SCHEMBL19089512 0.86 EGFR (0.56) EGFRERBB3DUS2KDRERBB2
SCHEMBL20656043 0.86 EGFR (0.52) EGFRERBB3DUS2KDRFGFR1
SCHEMBL20548833 0.86 EGFR (0.58) EGFRERBB3DUS2KDRFGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3398939-B1 ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY ANCUREALL PHARMACEUTICAL SHANGHAI CO LTD (CN) 2026-05-06 EP claimed
EP-3398939-B1 ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY ANCUREALL PHARMACEUTICAL SHANGHAI CO LTD (CN) 2026-05-06 EP disclosed