SCHEMBL35210345

SCHEMBL35210345

C=CC(=O)Nc1cc(Nc2cc(Nc3ccc(OC)c(Cl)c3)ncn2)c(OC)cc1OCCN(C)C

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
EGFR P00533 12/20 0.55
ERBB2 P04626 1/20 0.55
FGFR1 P11362 5/20 0.55
KDR P35968 2/20 0.51
ALK Q9UM73 1/20 0.49
ERBB3 P21860 1/20 0.49
DUS2 Q9NX74 1/20 0.49
FGFR4 P22455 2/20 0.49
FGFR2 P21802 1/20 0.48
FGFR3 P22607 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19089628 1.00 EGFR (0.55) EGFRERBB2FGFR1KDRALK
SCHEMBL20656043 0.93 EGFR (0.52) EGFRERBB2FGFR1KDRALK
SCHEMBL19089517 0.93 EGFR (0.59) EGFRERBB2FGFR1KDRERBB3
SCHEMBL35210320 0.93 EGFR (0.59) EGFRERBB2FGFR1KDRERBB3
SCHEMBL20548741 0.89 EGFR (0.55) EGFRERBB2FGFR1KDRFGFR4
SCHEMBL35210337 0.89 EGFR (0.55) EGFRERBB2FGFR1KDRFGFR4
SCHEMBL20655511 0.88 EGFR (0.60) EGFRALK
SCHEMBL20548915 0.85 EGFR (0.56) EGFRERBB2FGFR1KDRALK
SCHEMBL35210316 0.85 EGFR (0.56) EGFRERBB2FGFR1KDRALK
SCHEMBL19089546 0.83 EGFR (0.62) EGFRERBB2KDRERBB3DUS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3398939-B1 ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY ANCUREALL PHARMACEUTICAL SHANGHAI CO LTD (CN) 2026-05-06 EP claimed
EP-3398939-B1 ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY ANCUREALL PHARMACEUTICAL SHANGHAI CO LTD (CN) 2026-05-06 EP disclosed