SCHEMBL35210328

SCHEMBL35210328

C=CC(=O)Nc1cc(Nc2cc(Nc3ccc(O)c(Cl)c3)ncn2)c(OC)cc1N(C)CCN(C)C

nearest known ligand 0.59

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
EGFR P00533 20/20 0.59
ALK Q9UM73 4/20 0.56
EML4 Q9HC35 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20548947 1.00 EGFR (0.59) EGFRALKEML4
SCHEMBL35210327 1.00 EGFR (0.59) EGFRALKEML4
SCHEMBL20655511 0.94 EGFR (0.60) EGFRALKEML4
SCHEMBL20548919 0.91 EGFR (0.58) EGFRALKEML4
SCHEMBL35210335 0.91 EGFR (0.58) EGFRALKEML4
SCHEMBL19089564 0.90 EGFR (0.59) EGFRALKEML4
SCHEMBL20548847 0.89 EGFR (0.58) EGFRALKEML4
SCHEMBL35210287 0.89 EGFR (0.58) EGFRALKEML4
SCHEMBL20655715 0.89 EGFR (0.47) EGFRALKEML4
SCHEMBL20548752 0.89 EGFR (0.59) EGFRALKEML4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3398939-B1 ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY ANCUREALL PHARMACEUTICAL SHANGHAI CO LTD (CN) 2026-05-06 EP disclosed