SCHEMBL35210332

SCHEMBL35210332

CC1(C(O)c2ccccc2)CCN(CCOc2ccccc2C(F)(F)F)CC1

nearest known ligand 0.65

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 12/20 0.65
HTR1A P08908 1/20 0.48
HTR7 P34969 1/20 0.48
LTA4H P09960 2/20 0.47
PTGS2 P35354 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C19 P33261 1/20 0.47
HSD17B10 Q99714 1/20 0.47
DRD1 P21728 1/20 0.46
MEN1 O00255 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41
KDM4E B2RXH2 1/20 0.41
FAAH O00519 1/20 0.41
BCHE P06276 1/20 0.41
ACHE P22303 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17848521 1.00 DRD2 (0.65) DRD2HTR1AHTR7LTA4HPTGS2
SCHEMBL17848405 0.88 DRD2 (0.60) DRD2HTR1AHTR7LTA4HPTGS2
SCHEMBL17848384 0.83 DRD2 (0.71) DRD2HTR1AHTR7LTA4HPTGS2
SCHEMBL17848471 0.80 DRD2 (0.64) DRD2HTR1AHTR7LTA4HPTGS2
SCHEMBL17848612 0.79 DRD2 (0.77) DRD2HTR1AHTR7LTA4HPTGS2
SCHEMBL17848469 0.79 DRD2 (1.00) DRD2HTR1AHTR7LTA4HPTGS2
SCHEMBL17848435 0.78 DRD2 (0.65) DRD2HTR1AHTR7LTA4HPTGS2
SCHEMBL17848605 0.78 DRD2 (0.65) DRD2HTR1AHTR7LTA4HPTGS2
SCHEMBL29944219 0.78 DRD2 (0.65) DRD2HTR1AHTR7LTA4HPTGS2
SCHEMBL17848473 0.77 DRD2 (0.63) DRD2HTR1AHTR7LTA4HPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3233077-B1 DOPAMINE D2 RECEPTOR LIGANDS BROAD INST INC (US) 2026-05-06 EP disclosed