Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.52 |
| ▸ | DRD1 | P21728 | 5/20 | 0.44 |
| ▸ | DRD5 | P21918 | 5/20 | 0.44 |
| ▸ | HRH1 | P35367 | 5/20 | 0.44 |
| ▸ | DRD4 | P21917 | 4/20 | 0.44 |
| ▸ | DRD3 | P35462 | 4/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17848368 | 0.84 | DRD2 (0.72) | DRD2 | |
| SCHEMBL25467967 | 0.78 | TDP1 (0.54) | DRD2DRD4DRD3TSHR | |
| SCHEMBL17848548 | 0.77 | DRD2 (0.74) | DRD2TSHR | |
| SCHEMBL17848337 | 0.77 | DRD2 (0.61) | DRD2 | |
| SCHEMBL17848600 | 0.73 | DRD2 (0.59) | DRD2 | |
| SCHEMBL17848536 | 0.72 | DRD2 (0.68) | DRD2DRD1DRD5HRH1DRD4 | |
| SCHEMBL17861676 | 0.71 | DRD2 (0.72) | DRD2DRD1DRD5HRH1DRD4 | |
| SCHEMBL17848317 | 0.68 | DRD2 (0.72) | DRD2TSHR | |
| SCHEMBL17848547 | 0.68 | DRD2 (0.73) | DRD2 | |
| SCHEMBL17848469 | 0.68 | DRD2 (1.00) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233077-B1 | DOPAMINE D2 RECEPTOR LIGANDS | BROAD INST INC (US) | 2026-05-06 | — | — | EP | disclosed |