SCHEMBL35210378

SCHEMBL35210378

O=C1CC(c2ccccc2-c2ccncc2)CN1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 2/20 0.55
ADRA1D P25100 3/20 0.50
ADRA1A P35348 3/20 0.50
ADRA2A P08913 2/20 0.50
BRD4 O60885 1/20 0.42
CYP19A1 P11511 3/20 0.41
GAA P10253 1/20 0.40
MAPK14 Q16539 1/20 0.38
NPC1 O15118 2/20 0.38
TP53 P04637 2/20 0.38
MAPT P10636 2/20 0.38
RAB9A P51151 2/20 0.38
MAPK10 P53779 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
CDC7 O00311 1/20 0.37
ALDH1A1 P00352 2/20 0.37
HSD17B10 Q99714 1/20 0.37
IDO1 P14902 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1269156 0.77 MTNR1A (0.61) MTNR1AADRA1DADRA1AALDH1A1CYP1A2
SCHEMBL2458036 0.74 MTNR1A (0.54) MTNR1AGAAALDH1A1CYP1A2CYP2C19
SCHEMBL559693 0.74 MTNR1A (0.50) MTNR1ABRD4ALDH1A1CYP1A2CYP2C19
SCHEMBL23702862 0.74 MTNR1A (0.47) MTNR1ABRD4ALDH1A1CYP1A2CYP2C19
SCHEMBL29995242 0.74 MTNR1A (0.47) MTNR1ABRD4ALDH1A1CYP1A2CYP2C19
SCHEMBL23778971 0.73 MTNR1A (0.61) MTNR1ABRD4GAANPC1RAB9A
SCHEMBL10759562 0.73 MTNR1A (0.61) MTNR1AADRA1DADRA1ATP53MAPT
SCHEMBL2513645 0.73 MTNR1A (0.56) MTNR1ATP53MAPT
SCHEMBL2513644 0.73 MTNR1A (0.56) MTNR1ATP53MAPT
SCHEMBL13525298 0.73 MTNR1A (0.56) MTNR1ATP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4737448-A1 SARM1 ENZYME ACTIVITY INHIBITOR AND USE THEREOF Artivila (ShenZhen) Innovation Center, Ltd. (CN) 2026-05-06 EP disclosed