Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4058277 | 0.89 | POLB (0.40) | ALDH1A1HPGDSMN1; SMN2PPARGPOLB | |
| SCHEMBL17292167 | 0.84 | TSHR (0.42) | TSHRALDH1A1HPGDSMN1; SMN2RECQL | |
| SCHEMBL4622349 | 0.80 | SMN1; SMN2 (0.46) | ALDH1A1HPGDSMN1; SMN2HSD17B10MAPK1 | |
| SCHEMBL30001304 | 0.79 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2HSD17B10LMNAGAA | |
| SCHEMBL3360269 | 0.79 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2HSD17B10LMNAGAA | |
| SCHEMBL11582359 | 0.79 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTHSD17B10MAPK1PPARG | |
| SCHEMBL11582357 | 0.79 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTHSD17B10MAPK1PPARG | |
| SCHEMBL31556023 | 0.77 | SMN1; SMN2 (0.41) | TSHRALDH1A1SMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL29254324 | 0.77 | SMN1; SMN2 (0.42) | ALDH1A1SMN1; SMN2HSD17B10MAPK1POLB | |
| SCHEMBL7209148 | 0.77 | SMN1; SMN2 (0.42) | SMN1; SMN2PLA2G2APLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125384-A1 | INDAZOLE INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2026-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125384-A1 | INDAZOLE INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | CGAS, GMPS, PRKG1 | TSHR 1739/4885ALDH1A1 1171/4885HPGD 795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.