Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35210732 | 0.89 | TSHR (0.43) | POLBSMN1; SMN2HPGDKDM4EPPARG | |
| SCHEMBL4622349 | 0.83 | SMN1; SMN2 (0.46) | POLBSMN1; SMN2NPSR1HPGDALDH1A1 | |
| SCHEMBL17292410 | 0.82 | ALDH1A1 (0.37) | NPSR1HPGDKDM4EATMALDH1A1 | |
| SCHEMBL6443647 | 0.81 | POLB (0.38) | POLBSMN1; SMN2NPSR1HPGDKDM4E | |
| SCHEMBL6443648 | 0.81 | POLB (0.38) | POLBSMN1; SMN2NPSR1HPGDKDM4E | |
| SCHEMBL15330340 | 0.79 | ALDH1A1 (0.41) | HPGDKDM4EATMALDH1A1PTGER4 | |
| SCHEMBL15091742 | 0.79 | SMN1; SMN2 (0.37) | SMN1; SMN2NPSR1ALDH1A1CA12CA14 | |
| SCHEMBL15289820 | 0.79 | SMN1; SMN2 (0.37) | SMN1; SMN2NPSR1ALDH1A1CA12CA14 | |
| SCHEMBL20813495 | 0.78 | TSHR (0.44) | SMN1; SMN2NPSR1KDM4EALDH1A1CA12 | |
| SCHEMBL24964950 | 0.77 | SMN1; SMN2 (0.50) | POLBSMN1; SMN2NPSR1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009120358-A1 | OLIGOMER-NITROGENOUS BASE CONJUGATES | NEKTAR THERAPEUTICS (US) | 2009-10-01 | — | — | WO | disclosed |