Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.36 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15583603 | 0.89 | AAK1 (0.41) | AAK1CYP17A1RXFP1CA1CA2 | |
| SCHEMBL15511586 | 0.85 | AAK1 (0.39) | AAK1CYP17A1RXFP1CA1CA2 | |
| SCHEMBL16992932 | 0.85 | CYP17A1 (0.44) | AAK1CYP17A1RXFP1CA1CA2 | |
| SCHEMBL24157078 | 0.84 | ATR (0.42) | AAK1RXFP1BRD9METAP1LCK | |
| SCHEMBL31493121 | 0.84 | ATR (0.42) | AAK1RXFP1BRD9METAP1LCK | |
| SCHEMBL4790101 | 0.83 | MAP4K4 (0.39) | AAK1RXFP1CA1CA2BRD9 | |
| SCHEMBL20095391 | 0.82 | MEN1 (0.38) | AAK1RXFP1BRD9METAP1LCK | |
| SCHEMBL17336530 | 0.81 | AAK1 (0.42) | AAK1CYP17A1RXFP1CA1CA2 | |
| SCHEMBL30755583 | 0.81 | L3MBTL1 (0.41) | AAK1CYP17A1RXFP1METAP1LCK | |
| SCHEMBL594117 | 0.80 | CYP17A1 (0.40) | AAK1CYP17A1RXFP1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125389-A1 | MEMBRANE-ASSOCIATED TYROSINE AND THREONINE KINASE INHIBITOR AND USE THEREOF | HAINAN SIMCERE ZAIMING PHARMACEUTICAL CO LTD (CN) | 2026-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125389-A1 | MEMBRANE-ASSOCIATED TYROSINE AND THREONINE KINASE INHIBITOR AND USE THEREOF | PKMYT1, PKN1, ROS1 | AAK1 2016/4885CYP17A1 1812/4885RXFP1 884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.