Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 6/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30867239 | 0.81 | CHRM2 (0.38) | TACR1NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL35211212 | 0.81 | TACR1 (0.46) | TACR1NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL29770623 | 0.78 | NR1H2 (0.45) | TACR1NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL31603547 | 0.78 | NR1H2 (0.47) | TACR1NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL31603272 | 0.78 | NR1H2 (0.47) | TACR1NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL29770677 | 0.77 | NR1H2 (0.50) | TACR1NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL7407643 | 0.77 | NR1H2 (0.50) | TACR1NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL7407641 | 0.77 | NR1H2 (0.50) | TACR1NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL7407645 | 0.77 | NR1H2 (0.50) | TACR1NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL30079679 | 0.77 | NR1H2 (0.50) | TACR1NR1H2CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125391-A1 | PYRIMIDINE INDOLES AS CDK4 INHIBITORS | INCYTE CORP (US) | 2026-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125391-A1 | PYRIMIDINE INDOLES AS CDK4 INHIBITORS | CDK4, CCNA1, CCNO | TACR1 1587/4885NR1H2 804/4885CHRM2 4049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.