Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21341816 | 0.78 | CRHBP (0.34) | CRHBPCRHR2 | |
| SCHEMBL12458814 | 0.77 | GRIN2D (0.41) | — | |
| SCHEMBL15716234 | 0.76 | CRHBP (0.33) | CRHBPCRHR2 | |
| SCHEMBL14805863 | 0.73 | CRHBP (0.34) | CRHBPCRHR2 | |
| SCHEMBL16849087 | 0.72 | — | — | |
| SCHEMBL35211323 | 0.71 | CRHBP (0.33) | CRHBPCRHR2 | |
| SCHEMBL35211321 | 0.71 | CRHBP (0.33) | CRHBPCRHR2 | |
| SCHEMBL680047 | 0.71 | CRHBP (0.39) | CRHBPCRHR2 | |
| SCHEMBL12445299 | 0.71 | CRHBP (0.39) | CRHBPCRHR2 | |
| SCHEMBL12127018 | 0.69 | CRHBP (0.38) | CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125384-A1 | INDAZOLE INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2026-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125384-A1 | INDAZOLE INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | CGAS, GMPS, PRKG1 | CRHBP 2395/4885CRHR2 1270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.