SCHEMBL35211474

SCHEMBL35211474

Cn1c(C=O)nc2c(F)cc(F)cc21

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 2/20 0.34
PDE2A O00408 1/20 0.34
ERN1 O75460 1/20 0.33
ALDH1A1 P00352 3/20 0.32
HTT P42858 1/20 0.32
KDM4E B2RXH2 2/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TNKS O95271 1/20 0.31
PARP1 P09874 1/20 0.31
TNKS2 Q9H2K2 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TPSAB1 Q15661 1/20 0.30
TPSD1 Q9BZJ3 1/20 0.30
TPSG1 Q9NRR2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22894791 0.77 PDE10A (0.36) PDE10AERN1ALDH1A1HTTKDM4E
Hydrochloric Acid SCHEMBL5439722 0.74 PDE10A (0.34) PDE10AERN1ALDH1A1HTTKDM4E
SCHEMBL102290 0.73 PDE10A (0.34) PDE10APDE2ARAB9ASMN1; SMN2
SCHEMBL30885822 0.73
SCHEMBL30971771 0.72 ALOX15 (0.53) ALDH1A1HTTKDM4EHPGDRAB9A
SCHEMBL6870350 0.72 ALOX15 (0.53) ALDH1A1HTTKDM4EHPGDRAB9A
SCHEMBL35211324 0.71
SCHEMBL24402037 0.70
Hydrochloric Acid SCHEMBL4928225 0.70 ALOX15 (0.50) ALDH1A1HTTKDM4EHPGDRAB9A
SCHEMBL4777776 0.70 KDM4E (0.44) ALDH1A1KDM4EHPGDHSD17B10RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125366-A1 METHODS FOR TREATING CANCER SCORPION THERAPEUTICS INC (US) 2026-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125366-A1 METHODS FOR TREATING CANCER AKT2, AKT3, PIK3R5 PDE10A 898/4885PDE2A 845/4885ERN1 907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.