SCHEMBL35211475

SCHEMBL35211475

COc1cc2c3n(nc2c(F)c1Cl)CCN(C(=O)CNC(=O)OC(C)(C)C)C3C

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ FNTA P49354 2/20 0.35
▸ FNTB P49356 2/20 0.35
▸ BRD4 O60885 1/20 0.33
▸ CCNT1 O60563 2/20 0.32
▸ CDK9 P50750 2/20 0.32
▸ HDAC8 Q9BY41 1/20 0.32
▸ SUV39H2 Q9H5I1 4/20 0.32
▸ DRD2 P14416 3/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ TSHR P16473 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ MMP1 P03956 1/20 0.32
▸ MMP9 P14780 1/20 0.32
▸ MMP13 P45452 1/20 0.32
▸ TNF P01375 1/20 0.31
▸ LITAF Q99732 1/20 0.31
▸ SIGMAR1 Q99720 1/20 0.31
▸ P2RY12 Q9H244 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35211333 1.00 FNTA (0.35) FNTAFNTBBRD4CCNT1CDK9
SCHEMBL35211071 1.00 FNTA (0.35) FNTAFNTBBRD4CCNT1CDK9
SCHEMBL35210877 0.92 FNTA (0.36) FNTAFNTBBRD4HDAC8SUV39H2
SCHEMBL35211102 0.86 TLR9 (0.35) SUV39H2ALDH1A1TNFLITAF
SCHEMBL35211306 0.84 KMT2A (0.35) DRD2MEN1ALDH1A1KMT2A
SCHEMBL35211418 0.83 CCR1 (0.32) MEN1KMT2A
SCHEMBL35211347 0.83 CCR1 (0.32) MEN1KMT2A
SCHEMBL35211450 0.83 DPP4 (0.33) —
SCHEMBL35211078 0.83 DPP4 (0.33) —
SCHEMBL35211288 0.83 DPP4 (0.33) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125384-A1 INDAZOLE INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF VENTUS THERAPEUTICS U.S., INC. (US) 2026-05-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125384-A1 INDAZOLE INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF CGAS, GMPS, PRKG1 FNTA 2424/4885FNTB 1778/4885BRD4 3406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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