SCHEMBL35212210

SCHEMBL35212210

Fc1cc(Cl)ccc1N1CCCN(c2ccc(-c3ccc(OCc4ccccc4)nc3OCc3ccccc3)cc2F)CC1

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 4/20 0.42
GRM5 P41594 3/20 0.41
CNR1 P21554 7/20 0.40
DRD4 P21917 1/20 0.40
GRM2 Q14416 1/20 0.40
FFAR4 Q5NUL3 1/20 0.39
HTR1A P08908 1/20 0.37
HTR7 P34969 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31342590 0.89 FFAR4 (0.39) HRH4GRM5CNR1DRD4GRM2
SCHEMBL24753633 0.85 HTR1A (0.46) FFAR4HTR1A
SCHEMBL31342747 0.85 CNR1 (0.37) HRH4CNR1FFAR4
SCHEMBL31342671 0.85 CNR1 (0.37) HRH4CNR1FFAR4
SCHEMBL29013165 0.85 GRM5 (0.48) GRM5FFAR4
SCHEMBL30796430 0.85 GRM5 (0.41) GRM5FFAR4
SCHEMBL27452094 0.85 GRM5 (0.41) GRM5FFAR4
SCHEMBL30883480 0.84 HTR1A (0.38) HRH4GRM5FFAR4HTR1A
SCHEMBL25822642 0.83 MAPT (0.46) GRM5FFAR4
SCHEMBL25031334 0.82 FFAR4 (0.47) GRM5FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124309-A1 STAT6 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124309-A1 STAT6 DEGRADERS AND USES THEREOF STAT6, NCOR2, NCOR1 HRH4 55/4885GRM5 1981/4885CNR1 73/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.