⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34464975 | 0.85 | — | — | |
| SCHEMBL35211316 | 0.82 | USP30 (0.32) | — | |
| SCHEMBL34465221 | 0.82 | USP30 (0.32) | — | |
| SCHEMBL35212331 | 0.82 | USP30 (0.32) | — | |
| SCHEMBL34465127 | 0.82 | USP30 (0.32) | — | |
| SCHEMBL34466687 | 0.80 | PARP1 (0.33) | — | |
| SCHEMBL34466688 | 0.80 | PARP1 (0.33) | — | |
| SCHEMBL35212429 | 0.80 | PARP1 (0.33) | — | |
| SCHEMBL34465081 | 0.80 | PARP1 (0.33) | — | |
| SCHEMBL34464971 | 0.79 | USP30 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125383-A1 | INDAZOLE INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2026-05-07 | — | — | US | disclosed |