Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | KAT7 | O95251 | 1/20 | 0.32 |
| ▸ | KAT8 | Q9H7Z6 | 5/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 4/20 | 0.32 |
| ▸ | CETP | P11597 | 3/20 | 0.32 |
| ▸ | KAT5 | Q92993 | 3/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34466687 | 1.00 | PARP1 (0.33) | PARP1KAT7KAT8KAT6ACETP | |
| SCHEMBL35212429 | 1.00 | PARP1 (0.33) | PARP1KAT7KAT8KAT6ACETP | |
| SCHEMBL34466688 | 1.00 | PARP1 (0.33) | PARP1KAT7KAT8KAT6ACETP | |
| SCHEMBL34465061 | 0.91 | CNR1 (0.31) | USP30 | |
| SCHEMBL34465060 | 0.91 | CNR1 (0.31) | USP30 | |
| SCHEMBL35212586 | 0.91 | PARP1 (0.33) | PARP1KAT7KAT8KAT6ACETP | |
| SCHEMBL34465074 | 0.90 | USP30 (0.33) | USP30 | |
| SCHEMBL34466776 | 0.90 | PARP1 (0.34) | PARP1KAT7KAT8KAT6AKAT5 | |
| SCHEMBL35212331 | 0.90 | USP30 (0.32) | USP30 | |
| SCHEMBL34465127 | 0.90 | USP30 (0.32) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260108510-A1 | PYRAZOLYL INDAZOLE CGAS INHIBITORS AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2026-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260108510-A1 | PYRAZOLYL INDAZOLE CGAS INHIBITORS AND USES THEREOF | CGAS, GBA3, CYP11B2 | PARP1 762/4885KAT7 4120/4885KAT8 4116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.