Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 2/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.31 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.31 |
| ▸ | TNF | P01375 | 3/20 | 0.31 |
| ▸ | LITAF | Q99732 | 3/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35211102 | 0.89 | TLR9 (0.35) | TLR9DNMT3ANSD2SUV39H2ALDH1A1 | |
| SCHEMBL35212609 | 0.85 | EGFR (0.33) | EHMT2CCNT1CDK9 | |
| SCHEMBL35212559 | 0.85 | EGFR (0.33) | EHMT2CCNT1CDK9 | |
| SCHEMBL35212633 | 0.85 | EGFR (0.33) | EHMT2CCNT1CDK9 | |
| SCHEMBL34465741 | 0.84 | UCHL1 (0.33) | ALDH1A1LMNANR1H2NR1H3MAP4K4 | |
| SCHEMBL34466888 | 0.84 | UCHL1 (0.33) | ALDH1A1LMNANR1H2NR1H3MAP4K4 | |
| SCHEMBL35212041 | 0.84 | PDE4B (0.33) | TLR9DNMT3ANSD2SUV39H2PDE4B | |
| SCHEMBL35210758 | 0.83 | SUV39H2 (0.37) | TLR9NSD2SUV39H2PDE4BALDH1A1 | |
| SCHEMBL34466640 | 0.83 | SUV39H2 (0.37) | TLR9NSD2SUV39H2PDE4BALDH1A1 | |
| SCHEMBL35211325 | 0.83 | SUV39H2 (0.37) | TLR9NSD2SUV39H2PDE4BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125383-A1 | INDAZOLE INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2026-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125383-A1 | INDAZOLE INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | CGAS, PRKG1, GMPS | TLR9 3953/4885DNMT3A 2722/4885NSD2 4557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.