⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12585236 | 1.00 | — | — | |
| SCHEMBL1565515 | 0.72 | — | — | |
| SCHEMBL19337928 | 0.72 | — | — | |
| SCHEMBL18124555 | 0.72 | — | — | |
| SCHEMBL5527655 | 0.70 | — | — | |
| SCHEMBL17645066 | 0.70 | — | — | |
| SCHEMBL716179 | 0.70 | — | — | |
| SCHEMBL1565514 | 0.70 | — | — | |
| SCHEMBL822876 | 0.70 | — | — | |
| SCHEMBL198306 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114163564-B | Film-forming resin containing cholic acid-butenoate derivative and photoresist composition | 江苏集萃光敏电子材料研究所有限公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-114163564-A | Film-forming resin containing cholic acid-butenoate derivative and photoresist composition | 江苏集萃光敏电子材料研究所有限公司 | 2022-03-11 | — | — | CN | disclosed |
| EP-2721025-B1 | NEW SELECTIVE CCR2 ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2015-11-25 | — | — | EP | disclosed |
| EP-2721025-A1 | NEW SELECTIVE CCR2 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-04-23 | — | — | EP | disclosed |
| US-20130150354-A1 | NEW SELECTIVE CCR2 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-13 | — | — | US | disclosed |
| WO-2013010453-A1 | CHEMOKING RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2013-01-24 | — | — | WO | disclosed |
| WO-2012171863-A1 | NEW SELECTIVE CCR2 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-12-20 | — | — | WO | disclosed |
| EP-1682135-B1 | salt of a tetrahydropyranyl cyclopentyl tetrahydropyridopyridine derivative as CCR2-antagonist | MERCK SHARP & DOHME (US) | 2011-07-27 | — | — | EP | disclosed |
| US-7786305-B2 | Tetrahydropyranyl cyclopentyl tetrahydropyridopyridine modulators of chemokine receptor activity | MERCK SHARP & DOHME CORP. (US) | 2010-08-31 | — | — | US | disclosed |
| US-7473696-B2 | CCR-2 antagonist salt | MERCK & CO., INC. (US) | 2009-01-06 | — | — | US | disclosed |
| EP-1558243-A2 | TETRAHYDROPYRANYL CYCLOPENTYL BENZYLAMIDE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Merck & Co., Inc. (US) | 2005-08-03 | — | — | EP | disclosed |
| US-20050107422-A1 | Tetrahydropyranyl cyclopentyl tetrahydropyridopyridine modulators of chemokine receptor activity | MERCK SHARP & DOHME LLC | 2005-05-19 | — | — | US | disclosed |
| US-20050101628-A1 | Tetrahydropyranyl cyclopentyl tetrahydropyridopyridine modulators of chemokine receptor activity | MERCK SHARP & DOHME LLC | 2005-05-12 | — | — | US | disclosed |
| EP-1501803-A2 | TETRAHYDROPYRANYL CYCLOPENTYL TETRAHYDROISOQUINOLINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Merck & Co., Inc. (US) | 2005-02-02 | — | — | EP | disclosed |
| EP-1501507-A2 | TETRAHYDROPYRANYL CYCLOPENTYL TETRAHYDROPYRIDOPYRIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Merck & Co., Inc. (US) | 2005-02-02 | — | — | EP | disclosed |
| US-6812234-B2 | CCR-2; INFLAMMATORY, IMMUNOREGULATORY, ALLERGIC, AND AUTOIMMUNE DISORDERS AND DISEASES | MERCK & CO., INC. | 2004-11-02 | — | — | US | disclosed |
| US-20040167156-A1 | TETRAHYDROPYRANYL CYCLOPENTYL TETRAHYDROPYRIDOPYRIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK SHARP & DOHME LLC | 2004-08-26 | — | — | US | disclosed |
| WO-2004041161-A2 | TETRAHYDROPYRANYL CYCLOPENTYL BENZYLAMIDE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 2004-05-21 | — | — | WO | disclosed |
| WO-2003093231-A2 | TETRAHYDROPYRANYL CYCLOPENTYL TETRAHYDROISOQUINOLINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 2003-11-13 | — | — | WO | disclosed |
| WO-2003092586-A2 | TETRAHYDROPYRANYL CYCLOPENTYL TETRAHYDROPYRIDOPYRIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 2003-11-13 | — | — | WO | disclosed |