SCHEMBL3522072

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3525386	0.94	MAPT (0.43)	HSP90AA1MAPTMEN1KMT2AL3MBTL1
	SCHEMBL30599262	0.81	HSP90AB1 (0.50)	HSP90AA1HSP90AB1ERBB2HDAC3HDAC4
	SCHEMBL3122649	0.81	HSP90AB1 (0.50)	HSP90AA1HSP90AB1ERBB2HDAC3HDAC4
	SCHEMBL13845812	0.81	HSP90AB1 (0.37)	HSP90AA1HSP90AB1ERBB2HDAC3HDAC4
	SCHEMBL14067096	0.81	HSP90AA1 (0.43)	HSP90AA1HSP90AB1ERBB2HDAC3HDAC4
	SCHEMBL1858420	0.81	HSP90AA1 (0.50)	HSP90AA1HSP90AB1ERBB2HDAC3HDAC4
	SCHEMBL4903368	0.81	HSP90AA1 (0.50)	HSP90AA1HSP90AB1ERBB2HSP90B1TRAP1
	SCHEMBL11980469	0.78	HSP90AA1 (0.52)	HSP90AA1HSP90AB1ERBB2HDAC3HDAC4
	SCHEMBL3524045	0.78	HSP90AA1 (0.47)	HSP90AA1HSP90AB1ERBB2HDAC3HDAC4
	SCHEMBL16486867	0.78	PDE7A (0.50)	HSP90AA1MEN1KMT2APOLBHSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.