Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3326108 | 0.77 | CHRNA7 (0.51) | CHRNA7 | |
| SCHEMBL3327551 | 0.74 | CHRNA7 (0.58) | CHRNA7HTR3ACHRNA3HCRTR1HCRTR2 | |
| SCHEMBL3328505 | 0.74 | CHRNA7 (0.58) | CHRNA7HTR3ACHRNA3 | |
| Hydrochloric Acid SCHEMBL3327573 | 0.73 | CHRNA7 (0.57) | CHRNA7HTR3ACHRNA3HCRTR1HCRTR2 | |
| SCHEMBL4702689 | 0.70 | CHRNA7 (0.60) | CHRNA7HTR3A | |
| SCHEMBL3525014 | 0.70 | PBRM1 (0.39) | CHRNA7CHRNA3 | |
| SCHEMBL3331680 | 0.68 | CHRNA7 (1.00) | CHRNA7HTR3A | |
| SCHEMBL4700365 | 0.68 | CHRNA7 (0.51) | CHRNA7HTR3ACHRNA3 | |
| SCHEMBL4700143 | 0.68 | CHRNA7 (0.60) | CHRNA7HTR3ACHRNA3 | |
| SCHEMBL4703577 | 0.68 | CHRNA7 (0.53) | CHRNA7HTR3ACHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678788-B2 | Diazabicyclic aryl derivatives | NEUROSEARCH A/S (DK) | 2010-03-16 | — | — | US | disclosed |
| US-20060148789-A1 | Novel diazabicyclic aryl derivatives | NEUROSEARCH A/S (DK) | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148789-A1 | Novel diazabicyclic aryl derivatives | CHRNA6, CHRNA10, CHRNA2 | CHRNA7 6/4885HTR3A 237/4885CHRNA3 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.