SCHEMBL352555

SCHEMBL352555

O=C(O)C(O)c1ccc(O)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.65
MAPK1 P28482 1/20 0.65
SRC P12931 1/20 0.57
HIF1A Q16665 2/20 0.50
TSHR P16473 2/20 0.48
BLM P54132 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
ESR1 P03372 1/20 0.44
PDCD1 Q15116 1/20 0.44
ESR2 Q92731 1/20 0.44
CD274 Q9NZQ7 1/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA3 P07451 1/20 0.44
TYR P14679 1/20 0.44
DRD1 P21728 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
CA5A P35218 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL467741 1.00 LMNA (0.65) LMNAMAPK1SRCHIF1ATSHR
SCHEMBL31484031 1.00 LMNA (0.65) LMNAMAPK1SRCHIF1ATSHR
SCHEMBL1957930 1.00 LMNA (0.65) LMNAMAPK1SRCHIF1ATSHR
SCHEMBL5336172 0.98 LMNA (0.62) LMNAMAPK1SRCHIF1ATSHR
SCHEMBL7522519 0.98 LMNA (0.62) LMNAMAPK1SRCHIF1ATSHR
Water SCHEMBL564812 0.98 LMNA (0.62) LMNAMAPK1SRCHIF1ATSHR
SCHEMBL10954019 0.98 LMNA (0.62) LMNAMAPK1SRCHIF1ATSHR
Ammonia Solution, Strong SCHEMBL7530577 0.98 LMNA (0.62) LMNAMAPK1SRCHIF1ATSHR
SCHEMBL5088395 0.98 LMNA (0.62) LMNAMAPK1SRCHIF1ATSHR
SCHEMBL10957256 0.98 LMNA (0.62) LMNAMAPK1SRCHIF1ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2057 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3869192-B1 METHOD FOR QUANTITATIVE DETECTION OF VARIOUS METABOLITES IN BIOLOGICAL SAMPLE HUMAN METABOLOMICS INST INC (CN) 2026-05-13 EP claimed
CN-122004217-A Application of 4-hydroxy mandelic acid in prevention and control of bacterial wilt of plants 南京工业大学 2026-05-12 CN claimed
US-12558329-B2 Methods and compositions for treating 4-hydroxyphenylpyruvate dioxygenase-like (HPDL)-related diseases or disorders NEW YORK UNIVERSITY (US) 2026-02-24 US claimed
US-20250258146-A1 QUANTITATIVE DETECTION METHOD OF MULTIPLE METABOLITES IN BIOLOGICAL SAMPLE AND METABOLIC CHIP HUMAN METABOLOMICS INSTITUTE INC. (CN) 2025-08-14 US claimed
WO-2025137572-A1 COQ10 REPLETION USING 4-HMA NEW YORK UNIVERSITY (US) 2025-06-26 WO claimed
CN-120082497-A Method for producing L-phenylalanine, 4-hydroxymandelic acid and PHA material by one-carbon resource and application thereof 清华大学 2025-06-03 CN claimed
CN-120026047-A Microorganism with restructured aromatic amino acid metabolic pathway, construction method and application thereof 中国科学院青岛生物能源与过程研究所 2025-05-23 CN claimed
WO-2025054293-A1 BIOMARKER FOR PROSTATE CANCER NATIONAL TAIWAN UNIVERSITY (TW) 2025-03-13 WO claimed
US-20250076301-A1 BIOMARKER FOR PROSTATE CANCER NATIONAL TAIWAN UNIVERSITY (TW) 2025-03-06 US claimed
US-20250051551-A1 IMPROVED POLYMER COMPOSITES WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2025-02-13 US claimed
US-4363815-A Alpha hydroxyacids, alpha ketoacids and their use in treating skin conditions YU RUEY J 1982-12-14 US claimed
EP-0028375-B1 PROCESS FOR THE PREPARATION OF PHENYLACETIC ACID AND ITS SIMPLE DERIVATIVES HOECHST AKTIENGESELLSCHAFT (DE) 1982-12-08 EP claimed
EP-0008547-B1 PROCESS FOR THE PREPARATION OF R.S. 5-P-HYDROXYPHENYL-2,4-IMIDAZOLIDINE DIONE OR R.S. 5-P-HYDROXYPHENYL HYDANTOIN SOCIETE FRANCAISE HOECHST Société anonyme dite: (FR) 1982-11-10 EP claimed
US-4350826-A Process for preparing p-hydroxy phenylglycine IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1982-09-21 US claimed
US-4339594-A HYDROGENATION, HYDROGENATION CATALYSTS HOECHST AKTIENGESELLSCHAFT (DE) 1982-07-13 US claimed
US-4337355-A CATALYTIC REDUCTION OF 4-HYDROXYMANDELIC ACID, WATER-ALIPHATIC ACID MEDIUM NIPPON GOHSEI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1982-06-29 US claimed
EP-0024181-A1 Process for the isolation of a solid salt of p-hydroxymandelic acid; some salts of p-hydroxymandelic acid BEECHAM GROUP PLC (GB) 1981-02-25 EP claimed
WO-1981000404-A1 PROCESS FOR THE ISOLATION OF A SOLID SALT OF P-HYDROXY-MANDELIC ACID;SOME SALTS OF P-HYDROXYMANDELIC ACID BEECHAM GROUP LTD (GB) 1981-02-19 WO claimed
US-4198526-A REDUCTION FO P-HYDROXYMANDELIC ACID IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-04-15 US claimed
US-4110166-A CULTIVATION, CARBOXYLIC ACID FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1978-08-29 US claimed