Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | GRM8 | O00222 | 1/20 | 0.44 |
| ▸ | GRM6 | O15303 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL352654 | 1.00 | ALOX5 (0.47) | ALOX5HSD17B10TDP1MEN1CYP2C9 | |
| SCHEMBL3973896 | 1.00 | ALOX5 (0.47) | ALOX5HSD17B10TDP1MEN1CYP2C9 | |
| SCHEMBL3976361 | 0.83 | ALOX5 (0.51) | ALOX5SLC1A3SLC1A2SLC1A1LCK | |
| SCHEMBL8255743 | 0.83 | ALOX5 (0.51) | ALOX5SLC1A3SLC1A2SLC1A1LCK | |
| SCHEMBL4603992 | 0.83 | ALOX5 (0.51) | ALOX5SLC1A3SLC1A2SLC1A1LCK | |
| SCHEMBL10821116 | 0.82 | ALOX5 (0.46) | ALOX5SLC1A3SLC1A2SLC1A1LCK | |
| SCHEMBL4603985 | 0.82 | ALOX5 (0.46) | ALOX5SLC1A3SLC1A2SLC1A1LCK | |
| SCHEMBL11694264 | 0.82 | ALOX5 (0.46) | ALOX5CYP2D6SLC6A2SLC6A4SLC1A3 | |
| Hydrochloric Acid SCHEMBL11829834 | 0.80 | ALOX5 (0.45) | ALOX5CYP2D6SLC6A2SLC6A4SLC1A3 | |
| SCHEMBL11431774 | 0.79 | NR1I2 (0.50) | ALOX5TDP1MEN1CYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107337782-B | Cement-based material dispersant suitable for low-temperature construction and preparation method thereof | 江苏苏博特新材料股份有限公司 | 2021-04-20 | — | — | CN | claimed |
| US-5753619-A | CYCLIC HEPTAPEPTIDES FOR CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INSUSTRIES, LTD. (JP) | 1998-05-19 | — | — | US | claimed |
| EP-0714909-A1 | Composition for prophylaxis or treatment of pulmonary circulatory diseases | Takeda Chemical Industries, Ltd. (JP) | 1996-06-05 | — | — | EP | claimed |
| US-4073687-A | PENICILLINS OR CEPHALOSPORINS | SHIONOGI & CO., LTD. (JA) | 1978-02-14 | — | — | US | claimed |
| CN-107337782-B | Cement-based material dispersant suitable for low-temperature construction and preparation method thereof | 江苏苏博特新材料股份有限公司 | 2021-04-20 | — | — | CN | disclosed |
| US-10851119-B2 | Boron-containing diacylhydrazines | INTREXON CORPORATION (US) | 2020-12-01 | — | — | US | disclosed |
| US-20200157122-A1 | BORON-CONTAINING DIACYLHYDRAZINES | INTREXON CORP (US) | 2020-05-21 | — | — | US | disclosed |
| CN-107406373-B | Boron-containing diacylhydrazine compounds | 英特瑞克斯顿股份有限公司 | 2020-04-28 | — | — | CN | disclosed |
| EP-3194359-B1 | BORON-CONTAINING DIACYLHYDRAZINE COMPOUNDS | INTREXON CORP (US) | 2020-04-08 | — | — | EP | disclosed |
| US-10570158-B2 | Boron-containing diacylhydrazine compounds | INTREXON CORPORATION (US) | 2020-02-25 | — | — | US | disclosed |
| US-10464951-B2 | Boron-containing diacylhydrazines | INTREXON CORPORATION (US) | 2019-11-05 | — | — | US | disclosed |
| US-20180201628-A1 | Boron-Containing Diacylhydrazine Compounds | INTREXON CORP (US) | 2018-07-19 | — | — | US | disclosed |
| US-4029669-A | 6-Benzalimino-6-arylthio penicillanic acids and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1977-06-14 | — | — | US | disclosed |
| US-4026886-A | 7-Acyl-7-arylthiocephalosporins | E. R. SQUIBB & SONS, INC. (US) | 1977-05-31 | — | — | US | disclosed |
| US-3996219-A | BACTERICIDES | E. R. SQUIBB & SONS, INC. (US) | 1976-12-07 | — | — | US | disclosed |
| US-3996217-A | BACTERICIDES | E. R. SQUIBB & SONS, INC. (US) | 1976-12-07 | — | — | US | disclosed |
| US-3996218-A | BACTERICIDES | E. R. SQUIBB & SONS, INC. (US) | 1976-12-07 | — | — | US | disclosed |
| US-3994889-A | 3-Heterothio derivatives of (α-thiocarbonylaminol)-7α-methoxy-cephalosporins | E. R. SQUIBB & SONS, INC. (US) | 1976-11-30 | — | — | US | disclosed |
| US-3965093-A | 6-Arylthio penicillanic acid and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1976-06-22 | — | — | US | disclosed |
| US-3954744-A | ANTIBACTERIAL | E. R. SQUIBB & SONS, INC. (US) | 1976-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10464951-B2 | Boron-containing diacylhydrazines | CD22, BRDT, BCR | ALOX5 4644/4885HSD17B10 701/4885TDP1 2173/4885 |
| US-20180201628-A1 | Boron-Containing Diacylhydrazine Compounds | BRDT, CD22, BCR | ALOX5 4566/4885HSD17B10 823/4885TDP1 2048/4885 |
| US-10851119-B2 | Boron-containing diacylhydrazines | CD22, BRDT, BCR | ALOX5 4644/4885HSD17B10 701/4885TDP1 2173/4885 |
| US-20200157122-A1 | BORON-CONTAINING DIACYLHYDRAZINES | CD22, BRDT, BCR | ALOX5 4644/4885HSD17B10 701/4885TDP1 2173/4885 |
| US-10570158-B2 | Boron-containing diacylhydrazine compounds | BRDT, CD22, BCR | ALOX5 4566/4885HSD17B10 823/4885TDP1 2048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.