⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17186333 | 0.98 | NPC1 (0.56) | — | |
| SCHEMBL29551662 | 0.91 | ACP1 (0.61) | — | |
| SCHEMBL9275105 | 0.86 | NPC1 (0.56) | — | |
| Iodide SCHEMBL29079280 | 0.84 | NPC1 (0.54) | — | |
| SCHEMBL17993532 | 0.81 | ACP1 (0.61) | — | |
| SCHEMBL7375 | 0.81 | — | — | |
| SCHEMBL10486380 | 0.80 | RAB9A (0.46) | — | |
| SCHEMBL3524273 | 0.80 | ACP1 (0.62) | — | |
| SCHEMBL9212252 | 0.79 | HTT (0.62) | — | |
| SCHEMBL1468540 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 306 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107880038-A | [1,2,4] triazolo [1,5-a ] pyridine compound and preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2018-04-06 | — | — | CN | claimed |
| EP-2847192-A1 | NAMPT INHIBITORS | AbbVie Inc. (US) | 2015-03-18 | — | — | EP | claimed |
| WO-2013170112-A1 | NAMPT INHIBITORS | ABBVIE INC. (US) | 2013-11-14 | — | — | WO | claimed |
| CN-102905517-A | Gene switch compositions and methods of use | PIONEER HI BRED INT | 2013-01-30 | — | — | CN | claimed |
| CN-101636073-A | The seed of bag quilt and manufacturing bag are by the method for seed | VAMTECH L L C | 2010-01-27 | — | — | CN | claimed |
| WO-2009017454-A1 | NEW THERAPEUTIC COMBINATION OF A GSK3 INHIBITOR AND AN A7-NICOTINIC AGONIST 960 | ASTRAZENECA AB (SE) | 2009-02-05 | — | — | WO | claimed |
| WO-2009017455-A1 | A NEW COMBINATION OF (A) AN ALPHA-4-BETA-2 -NEURONAL NICOTINIC AGONIST AND (B) A GSK3 INHIBITOR | ASTRAZENECA AB (SE) | 2009-02-05 | — | — | WO | claimed |
| WO-2009017453-A1 | NEW THERAPEUTIC COMBINATION OF AN ANTIPSYCHOTIC AND A GSK3 INHIBITOR 958 | ASTRAZENECA AB (SE) | 2009-02-05 | — | — | WO | claimed |
| CN-1273466-C | Quinoline derivatives and quinazoline derivatives having azolyl group | KIRIN BREWERY (JP) | 2006-09-06 | — | — | CN | claimed |
| CN-1543459-A | Quinoline derivative and quinazoline derivative having azolyl group | ������������ʽ���� | 2004-11-03 | — | — | CN | claimed |
| WO-2003093250-A2 | POSITIVE ALLOSTERIC MODULATORS OF THE NICOTINIC ACETYLCHOLINE RECEPTOR | PHARMACIA & UPJOHN COMPANY (US) | 2003-11-13 | — | — | WO | claimed |
| US-20030187040-A1 | 2-Ureido-thiazole derivatives, process for their preparation, and their use as antitumor agents | PHARMACIA & UPJOHN SPA (IT) | 2003-10-02 | — | — | US | claimed |
| EP-0612215-B1 | PLANT CONTROL COMPOSITION AND METHODS OF USE | ENTEK CORP (US) | 1999-03-17 | — | — | EP | claimed |
| CN-1157617-A | Heterobicyclic derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-08-20 | — | — | CN | claimed |
| EP-0612215-A1 | PLANT CONTROL COMPOSITION AND METHODS OF USE | Entek Corporation (US) | 1994-08-31 | — | — | EP | claimed |
| WO-1993008691-A1 | PLANT CONTROL COMPOSITION AND METHODS OF USE | UNION OIL COMPANY OF CALIFORNIA (US) | 1993-05-13 | — | — | WO | claimed |
| CN-1071805-A | Plant coutrol composition and using method thereof | UNION OIL CO (US) | 1993-05-12 | — | — | CN | claimed |
| EP-0069784-B1 | THIAZOLYLUREA DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND MEDICINAL COMPOSITION CONTAINING SAME | MITSUI TOATSU KAGAKU KABUSHIKI KAISHA (JP) | 1987-12-16 | — | — | EP | claimed |
| US-4490393-A | Thiazolylurea derivatives, a process for preparing same and a pharmaceutical composition containing same | Mitsui Toatsu Kagaki Kabushiki Kaisha (JP) | 1984-12-25 | — | — | US | claimed |
| EP-0069784-A1 | THIAZOLYLUREA DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND MEDICINAL COMPOSITION CONTAINING SAME | MITSUI TOATSU KAGAKU KABUSHIKI KAISHA (JP) | 1983-01-19 | — | — | EP | claimed |