Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 3/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3527323 | 0.87 | GRM5 (0.37) | GRM5TNIKCSNK2A1 | |
| SCHEMBL2826274 | 0.84 | GRM5 (0.46) | GRM5TNIKCSNK2A1 | |
| SCHEMBL5185506 | 0.78 | GRM5 (0.47) | GRM5 | |
| SCHEMBL2829709 | 0.76 | CSNK2A1 (0.43) | GRM5CSNK2A1CSF1R | |
| SCHEMBL2830963 | 0.73 | CSNK2A1 (0.45) | GRM5CSNK2A1 | |
| SCHEMBL2829111 | 0.73 | GRM5 (0.50) | GRM5 | |
| SCHEMBL2827195 | 0.73 | GRM5 (0.47) | GRM5CSNK2A1 | |
| SCHEMBL2827045 | 0.72 | GRM5 (0.51) | GRM5CSNK2A1 | |
| SCHEMBL2828923 | 0.69 | GRM5 (0.46) | GRM5 | |
| SCHEMBL2830060 | 0.69 | ALDH1A1 (0.38) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678815-B2 | Thiazole-4-carboxyamide derivatives | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |