SCHEMBL35276

SCHEMBL35276

O=[N+]([O-])c1ccc(F)c([N+](=O)[O-])c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 1.00
HIF1A Q16665 2/20 1.00
TDP1 Q9NUW8 4/20 0.61
VCAM1 P19320 1/20 0.60
GPR35 Q9HC97 3/20 0.59
TSHR P16473 3/20 0.59
HPGD P15428 2/20 0.59
MAPK1 P28482 2/20 0.59
TP53 P04637 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
TXNRD1 Q16881 1/20 0.57
TXNRD3 Q86VQ6 1/20 0.57
TXNRD2 Q9NNW7 1/20 0.57
HSPB1 P04792 3/20 0.56
ATM Q13315 1/20 0.50
CYP1A2 P05177 2/20 0.49
HSD17B10 Q99714 2/20 0.48
MAPT P10636 2/20 0.48
KDM4E B2RXH2 1/20 0.48
MEN1 O00255 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29349904 1.00 ALDH1A1 (1.00) ALDH1A1HIF1ATDP1VCAM1GPR35
SCHEMBL27715742 1.00 ALDH1A1 (1.00) ALDH1A1HIF1ATDP1VCAM1GPR35
SCHEMBL28309178 0.98 ALDH1A1 (0.96) ALDH1A1HIF1ATDP1VCAM1GPR35
Benzene SCHEMBL28794915 0.96 ALDH1A1 (0.92) ALDH1A1HIF1ATDP1VCAM1GPR35
Methyl Alcohol SCHEMBL27725897 0.94 ALDH1A1 (0.89) ALDH1A1HIF1ATDP1VCAM1GPR35
Methylene Chloride SCHEMBL28308391 0.92 ALDH1A1 (0.85) ALDH1A1HIF1ATDP1VCAM1GPR35
Acetone SCHEMBL27892886 0.91 ALDH1A1 (0.82) ALDH1A1HIF1ATDP1VCAM1GPR35
Alcohol SCHEMBL27914560 0.89 ALDH1A1 (0.79) ALDH1A1HIF1ATDP1VCAM1GPR35
Acetonitrile SCHEMBL27709629 0.89 ALDH1A1 (0.79) ALDH1A1HIF1ATDP1VCAM1GPR35
SCHEMBL28285059 0.89 ALDH1A1 (0.79) ALDH1A1HIF1ATDP1VCAM1GPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8447 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12474347-B2 Determination of protein information by recoding amino acid polymers into DNA polymers ABRUS BIO, INC. (US) 2025-11-18 US claimed
US-20250311707-A1 TRANSGENIC MOUSE MODELS OF HUMAN ADAPTIVE AND INNATE IMMUNITY AND METHODS OF USE THE JACKSON LABORATORY (US) 2025-10-09 US claimed
US-20250243291-A1 PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES GENENTECH, INC. (US) 2025-07-31 US claimed
EP-4573372-A2 DETERMINATION OF PROTEIN INFORMATION BY RECODING AMINO ACID POLYMERS INTO DNA POLYMERS Abrus Bio, Inc. (US) 2025-06-25 EP claimed
CN-120041312-A Antiallergic Kluyveromyces marxianus, microbial inoculum, preparation and application thereof 安琪酵母股份有限公司 2025-05-27 CN claimed
EP-4555134-A2 DETERMINATION OF PROTEIN INFORMATION BY RECODING AMINO ACID POLYMERS INTO DNA POLYMERS Abrus Bio, Inc. (US) 2025-05-21 EP claimed
CN-119790193-A Determination of protein information by recoding amino acid polymers into DNA polymers 阿布鲁斯生物公司 2025-04-08 CN claimed
WO-2025064602-A1 REDOX TRAPPING USEFUL FOR BIOSPECIMEN PRESERVATION WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) 2025-03-27 WO claimed
WO-2025059964-A1 METHOD FOR PREPARING ANTIGEN-DELIVERY PARTICLE 苏州尔生生物医药有限公司 2025-03-27 WO claimed
EP-4365189-B1 PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES HOFFMANN LA ROCHE (CH) 2025-02-19 EP claimed
EP-0177191-A1 Methods of assay SERONO DIAGNOSTICS PARTNERS (A MASSACHUSETTS LIMITED PARTNERSHIP) (US) 1986-04-09 EP claimed
EP-0155854-A2 Non-radioactive biological probes BRESATEC LIMITED (AU) 1985-09-25 EP claimed
EP-0148193-A1 METHOD AND REAGENT FOR THE DETERMINATION OF ANGIOTENSIN CONVERTING ENZYME. BOEHRINGER MANNHEIM GMBH (DE) 1985-07-17 EP claimed
EP-0127079-A1 Process for preparing 2-fluoro-5-nitroaniline SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-12-05 EP claimed
WO-1984004331-A1 METHOD AND REAGENT FOR THE DETERMINATION OF ANGIOTENSIN CONVERTI NG ENZYME BOEHRINGER MANNHEIM GMBH (DE) 1984-11-08 WO claimed
EP-0119448-A1 Oligonucleotide derivatives and production thereof WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1984-09-26 EP claimed
US-4214592-A Patch for skin tests INSTITUT MERIEUX (FR) 1980-07-29 US claimed
US-4200508-A Method and composition for detecting antigenic substances HIRAI HIDEMATSU (JP) 1980-04-29 US claimed
US-4170708-A FROM AN AROMATIC NITRO COMPOUND, AN ALCOHOL, AND CARBON MONOXIDE MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1979-10-09 US claimed
US-3959078-A Enzyme immobilization with a thermochemical-photochemical bifunctional agent MIDWEST RESEARCH INSTITUTE (US) 1976-05-25 US claimed