SCHEMBL352842

SCHEMBL352842

NC(N)(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.64
SLC6A2 P23975 1/20 0.64
SMN1; SMN2 Q16637 2/20 0.56
HIF1A Q16665 1/20 0.56
CYP1A2 P05177 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
LOXL2 Q9Y4K0 2/20 0.48
LMNA P02545 1/20 0.46
CYP2D6 P10635 1/20 0.46
MAOB P27338 3/20 0.46
MAOA P21397 2/20 0.46
CALM1 P0DP23 1/20 0.45
AOC3 Q16853 1/20 0.44
CYP2A6 P11509 1/20 0.43
HTR2A P28223 1/20 0.43
FDPS P14324 1/20 0.43
KIF11 P52732 1/20 0.42
IDO1 P14902 3/20 0.42
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10503241 0.85 TAAR1 (0.67) TAAR1SLC6A2SMN1; SMN2HIF1ACYP1A2
SCHEMBL9860207 0.85 TAAR1 (0.60) TAAR1SLC6A2SMN1; SMN2HIF1ACYP1A2
SCHEMBL4081566 0.82 TAAR1 (0.64) TAAR1SLC6A2SMN1; SMN2HIF1ACYP1A2
SCHEMBL583541 0.82 TAAR1 (0.64) TAAR1SLC6A2SMN1; SMN2HIF1ACYP1A2
Hydrochloric Acid SCHEMBL5087218 0.80 TAAR1 (0.61) TAAR1SLC6A2SMN1; SMN2HIF1ACYP1A2
Water SCHEMBL8366271 0.80 TAAR1 (0.61) TAAR1SLC6A2SMN1; SMN2HIF1ACYP1A2
Bromide SCHEMBL5087806 0.80 TAAR1 (0.61) TAAR1SLC6A2SMN1; SMN2HIF1ACYP1A2
Iodide SCHEMBL5092148 0.80 TAAR1 (0.61) TAAR1SLC6A2SMN1; SMN2HIF1ACYP1A2
Phentermine SCHEMBL26615 0.78 SLC6A2 (1.00) TAAR1SLC6A2SMN1; SMN2HIF1ACYP1A2
SCHEMBL2573964 0.78 TAAR1 (0.58) TAAR1SLC6A2SMN1; SMN2HIF1ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118084793-A Diamine monomer containing imidazole structure, and preparation method and application thereof 波米科技有限公司 2024-05-28 CN claimed
US-20080281112-A1 Diamine and polyamic acid derived therefrom for liquid crystal orientation applications DAILY POLYMER CO., LTD. 2008-11-13 US claimed
US-20080058496-A1 Polyamic acid-based composition, and liquid crystal orienting agent and orienting film containing the same DAILY POLYMER CO., LTD. 2008-03-06 US claimed
EP-0607976-B1 Alignment treating agent for liquid crystal cell NISSAN CHEMICAL IND LTD (JP) 2002-11-13 EP claimed
US-6441127-B1 COMPRISING A POLYIMIDE FOR A SUPER-TWISTED NEMATIC LIQUID CRYSTAL CELL, DERIVED FROM UNITS OF AROMATIC DIAMINES AND SPECIFIED TETRACARBOXYLIC ACIDS SUCH AS PYROMELLITIC ACID NISSAN CHEMICAL INDUSTRIES LTD. (JP) 2002-08-27 US claimed
US-6139917-A Liquid crystal aligning agent NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2000-10-31 US claimed
EP-0564009-B1 Electric and electronic devices having a polyimide resin insulating film NISSAN CHEMICAL IND LTD (JP) 1997-09-17 EP claimed
EP-0540829-B1 Novel liquid crystal alignment treating agent NISSAN CHEMICAL IND LTD (JP) 1997-02-26 EP claimed
EP-0527439-B1 Alignment treating agent for liquid crystal cell NISSAN CHEMICAL IND LTD (JP) 1996-05-29 EP claimed
US-5350539-A Alignment treating agent for liquid crystal cell NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1994-09-27 US claimed
EP-0607976-A1 Alignment treating agent for liquid crystal cell NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1994-07-27 EP claimed
US-5298590-A Polyamide resin consisting diamine including aromatic diamine having at least one linear alkyl group NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1994-03-29 US claimed
EP-0564009-A1 Electric and electronic devices having a polyimide resin insulating film NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1993-10-06 EP claimed
EP-0540829-A1 Novel liquid crystal alignment treating agent NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1993-05-12 EP claimed
EP-0527439-A1 Alignment treating agent for liquid crystal cell NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1993-02-17 EP claimed
US-5070182-A CYCLOBUTANETETRACARBOXYLIC ACID MONOMER NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1991-12-03 US claimed
EP-0249881-B1 LIQUID CRYSTAL ALIGNING AGENT NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1990-10-03 EP claimed
US-RE33342-E Liquid crystal aligning agent from tetracarboxylic acid dianhydride, diamine and monoamine NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1990-09-18 US claimed
US-4749777-A POLYIMIDE FILMS NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1988-06-07 US claimed
EP-0249881-A1 Liquid crystal aligning agent NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1987-12-23 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080281112-A1 Diamine and polyamic acid derived therefrom for liquid crystal orientation applications DAO, F12, PARG TAAR1 1446/4885SLC6A2 3753/4885SMN1; SMN2 3803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.