SCHEMBL4081566

SCHEMBL4081566

NC(Cc1ccccc1)(Cc1ccccc1)C(N)(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.64
SLC6A2 P23975 1/20 0.64
SMN1; SMN2 Q16637 2/20 0.62
HIF1A Q16665 1/20 0.62
FDPS P14324 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
LOXL2 Q9Y4K0 2/20 0.48
LMNA P02545 1/20 0.46
CYP2D6 P10635 1/20 0.46
MAOB P27338 3/20 0.46
MAOA P21397 2/20 0.46
CALM1 P0DP23 1/20 0.45
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA5A P35218 1/20 0.44
CA9 Q16790 1/20 0.44
CYP2A6 P11509 1/20 0.43
HTR2A P28223 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4970864 0.86 SMN1; SMN2 (0.50) TAAR1SLC6A2SMN1; SMN2HIF1AFDPS
SCHEMBL10503241 0.85 TAAR1 (0.67) TAAR1SLC6A2SMN1; SMN2HIF1AFDPS
SCHEMBL9055685 0.85 SLC6A2 (0.67) TAAR1SLC6A2SMN1; SMN2HIF1ACYP1A2
SCHEMBL583541 0.82 TAAR1 (0.64) TAAR1SLC6A2SMN1; SMN2HIF1AFDPS
SCHEMBL352842 0.82 TAAR1 (0.64) TAAR1SLC6A2SMN1; SMN2HIF1AFDPS
Water SCHEMBL8366271 0.80 TAAR1 (0.61) TAAR1SLC6A2SMN1; SMN2HIF1AFDPS
Iodide SCHEMBL5092148 0.80 TAAR1 (0.61) TAAR1SLC6A2SMN1; SMN2HIF1AFDPS
Hydrochloric Acid SCHEMBL5087218 0.80 TAAR1 (0.61) TAAR1SLC6A2SMN1; SMN2HIF1AFDPS
Bromide SCHEMBL5087806 0.80 TAAR1 (0.61) TAAR1SLC6A2SMN1; SMN2HIF1AFDPS
SCHEMBL10580949 0.79 SMN1; SMN2 (0.48) TAAR1SLC6A2SMN1; SMN2HIF1AFDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112679431-A Method for preparing isoquinolone compound 上海迪赛诺化学制药有限公司 2021-04-20 CN claimed
EP-0383089-B1 Cold curing reactive resin blend and its use BAYER AG (DE) 1994-04-06 EP claimed
US-5084544-A Reaction of polyepoxides and polyisocyanates to form polyurethanes BAYER AKTIENGESELLSCHAFT (DE) 1992-01-28 US claimed
EP-0383089-A2 Cold curing reactive resin blend and its use BAYER AG (DE) 1990-08-22 EP claimed
CN-115353667-A Method and material for reducing waste 李蓁蓁 2022-11-18 CN disclosed
CN-112679431-A Method for preparing isoquinolone compound 上海迪赛诺化学制药有限公司 2021-04-20 CN disclosed
CN-108558676-B Preparation method of N, N-dibenzylethylenediamine diacetate 四川武胜春瑞医药化工有限公司 2021-01-19 CN disclosed
CN-107091689-B Ultraviolet sensing layer coating liquid 富士胶片株式会社 2020-06-05 CN disclosed
US-10247603-B2 Ultraviolet-sensitive sheet, ultraviolet-sensing kit, and method for sensing ultraviolet FUJIFILM CORPORATION (JP) 2019-04-02 US disclosed
CN-106537103-B Ultraviolet light perception tablet, ultraviolet light perception set group and ultraviolet light cognitive method 富士胶片株式会社 2019-03-01 CN disclosed
US-10203245-B2 Ultraviolet-sensitive sheet, method for manufacturing ultraviolet-sensing sheet, and method for sensing ultraviolet FUJIFILM CORPORATION (JP) 2019-02-12 US disclosed
US-10113907-B2 Ultraviolet-sensing sheet, ultraviolet-sensing set, and ultraviolet-sensing method FUJIFILM CORPORATION (JP) 2018-10-30 US disclosed
US-5750804-A HYDROGENATING 3-ISOCAMPHYLCYCLOHEXANONE USING RUTHENIUM/PHOSPHINE COMPLEX CATALYST IN PRESENCE OF ALKALI METAL OR ALKALINE EARTH METAL AND AMINE BASE TAKASAGO INTERNATIONAL CORPORATION (JP) 1998-05-12 US disclosed
EP-0829463-A2 (E)-(R)-2-Alkyl-4-(2,2,3-trimethylcyclopent-3-en-1-yl)-2-buten-1-ol, process for preparing the same, and use thereof in perfume compositions Takasago International Corporation (JP) 1998-03-18 EP disclosed
US-5059391-A USE OF POLYARALKYLAMINES AS CORROSION INHIBITORS BAYER AKTIENGESELLSCHAFT (DE) 1991-10-22 US disclosed
US-4996537-A Method of and apparatus for recording image FUJI PHOTO FILM CO., LTD. (JP) 1991-02-26 US disclosed
US-4962009-A DRY IMAGE FORMING FUJI PHOTO FILM CO., LTD. (JP) 1990-10-09 US disclosed
US-4942107-A Image-forming material and image recording method using the same FUJI PHOTO FILM CO., LTD. (JP) 1990-07-17 US disclosed
US-4929530-A OXIDATIVE LEUCO DYES, PHOTO-OXIDIZERS, REDUCING AGENTS, ORGANIC SULFONAMIDES AND PHENOLIC COMPONENTS; EXPOSING TO LIGHT FUJI PHOTO FILM CO., LTD. (JP) 1990-05-29 US disclosed
EP-0012587-B1 THERMO-SENSITIVE MULTI-COLOR RECORDING MATERIAL AND PROCESS FOR PREPARATION THEREOF Ricoh Company, Ltd (JP) 1983-05-25 EP disclosed