SCHEMBL3528797

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3531899	0.85	CHRM2 (0.43)	AURKANTRK1LCKKDRKDM4E
	SCHEMBL3529221	0.82	ALDH1A1 (0.53)	AURKAKDM4EALDH1A1TSHR
	SCHEMBL3531279	0.82	AURKA (0.51)	AURKANTRK1LCKITK
	SCHEMBL3533447	0.82	NTRK1 (0.45)	NTRK1LCKKDRITKWNK1
	SCHEMBL3530183	0.82	ALDH1A1 (0.45)	AURKANTRK1KDRALDH1A1TSHR
	SCHEMBL3531462	0.81	CYP2D6 (0.46)	AURKANTRK1KDRALDH1A1TSHR
	SCHEMBL3531608	0.81	AURKA (0.43)	AURKANTRK1LCKKDRALDH1A1
	SCHEMBL3532011	0.81	NTRK1 (0.44)	AURKANTRK1LCKKDRALDH1A1
	SCHEMBL3535502	0.81	NTRK1 (0.46)	NTRK1LCKKDRITKWNK1
	SCHEMBL3532033	0.81	NTRK1 (0.42)	AURKANTRK1LCKKDRITK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.