Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.55 |
| ▸ | CES1 | P23141 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 7/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RARA | P10276 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoyl Peroxide SCHEMBL6063535 | 0.86 | CES2 (0.54) | CES2CES1MEN1KMT2AKDM4E | |
| Benzamide SCHEMBL8749545 | 0.86 | CES2 (0.54) | CES2CES1MEN1KMT2AKDM4E | |
| Phthalic Acid SCHEMBL29031194 | 0.86 | MEN1 (0.63) | CES2CES1MEN1KMT2AKDM4E | |
| Benzoic Acid SCHEMBL3529350 | 0.85 | CES2 (0.56) | CES2CES1MEN1KMT2AKDM4E | |
| Benzoic Acid SCHEMBL11099565 | 0.85 | CES2 (0.56) | CES2CES1MEN1KMT2AKDM4E | |
| Benzoic Acid SCHEMBL5273323 | 0.85 | CES2 (0.56) | CES2CES1MEN1KMT2AKDM4E | |
| Benzoic Acid SCHEMBL25427629 | 0.84 | CES2 (0.55) | CES2CES1MEN1KMT2AKDM4E | |
| Benzoic Acid SCHEMBL27458611 | 0.84 | CES2 (0.55) | CES2CES1MEN1KMT2AKDM4E | |
| Benzoic Acid SCHEMBL28140499 | 0.84 | CES2 (0.55) | CES2CES1MEN1KMT2AKDM4E | |
| Benzoic Acid SCHEMBL2380641 | 0.84 | CES2 (0.55) | CES2CES1TP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10150931-B2 | Grease compositions comprising estolide base oils | BIOSYNTHETIC TECHNOLOGIES, LLC (US) | 2018-12-11 | — | — | US | disclosed |
| US-20170233676-A1 | Grease Compositions Comprising Estolide Base Oils | BIOSYNTHETIC TECHNOLOGIES LLC (US) | 2017-08-17 | — | — | US | disclosed |
| US-9605231-B2 | Grease compositions comprising estolide base oils | BIOSYNTHETIC TECHNOLOGIES, LLC (US) | 2017-03-28 | — | — | US | disclosed |
| US-20160281023-A1 | Grease Compositions Comprising Estolide Base Oils | BIOSYN HOLDINGS, LLC | 2016-09-29 | — | — | US | disclosed |
| US-9394501-B2 | Grease compositions comprising estolide base oils | BIOSYNTHETIC TECHNOLOGIES, LLC (US) | 2016-07-19 | — | — | US | disclosed |
| EP-2702122-A1 | GREASE COMPOSITIONS COMPRISING ESTOLIDE BASE OILS | Biosynthetic Technologies, LLC (US) | 2014-03-05 | — | — | EP | disclosed |
| US-20120322707-A1 | GREASE COMPOSITIONS COMPRISING ESTOLIDE BASE OILS | BIOSYN HOLDINGS, LLC | 2012-12-20 | — | — | US | disclosed |
| WO-2012173665-A1 | GREASE COMPOSITIONS COMPRISING ESTOLIDE BASE OILS | LUBRIGREEN BIOSYNTHETICS, LLC (US) | 2012-12-20 | — | — | WO | disclosed |
| EP-2205707-A1 | LUBRICATING GREASE COMPOSITION AND PREPARATION | Chevron U.S.A., Inc. (US) | 2010-07-14 | — | — | EP | disclosed |
| WO-2009042507-A1 | LUBRICATING GREASE COMPOSITION AND PREPARATION | CHEVRON U.S.A. INC. (US) | 2009-04-02 | — | — | WO | disclosed |
| US-20090088353-A1 | LUBRICATING GREASE COMPOSITION AND PREPARATION | CHEVRON U.S.A. INC. | 2009-04-02 | — | — | US | disclosed |
| US-20090088354-A1 | LUBRICATING GREASE COMPOSITION AND PREPARATION | CHEVRON U.S.A. INC. | 2009-04-02 | — | — | US | disclosed |
| US-20070238625-A1 | Grease Composition And Additive For Improving Bearing Life | AFTON CHEMICAL CORPORATION | 2007-10-11 | — | — | US | disclosed |
| EP-1842897-A1 | Grease composition and additive for improving bearing life | Afton Chemical Corporation (US) | 2007-10-10 | — | — | EP | disclosed |
| US-5037563-A | Addition of calcium oxide | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1991-08-06 | — | — | US | disclosed |