SCHEMBL352974

SCHEMBL352974

O=c1cc(O)ccn1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.59
SLC28A2 O43868 1/20 0.59
SLC29A1 Q99808 1/20 0.59
SLC28A3 Q9HAS3 1/20 0.59
LMNA P02545 2/20 0.56
MTOR P42345 2/20 0.56
THRB P10828 1/20 0.56
MDM2 Q00987 1/20 0.56
NCOA1 Q15788 1/20 0.56
NCOA3 Q9Y6Q9 1/20 0.56
MAPT P10636 1/20 0.53
CDA P32320 1/20 0.53
SLC5A2 P31639 2/20 0.48
ALDH1A1 P00352 2/20 0.47
HTT P42858 2/20 0.47
BLM P54132 2/20 0.47
GMNN O75496 1/20 0.47
TP53 P04637 1/20 0.47
NFKB1 P19838 1/20 0.47
DNMT1 P26358 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12594002 1.00 SLC28A1 (0.59) SLC28A1SLC28A2SLC29A1SLC28A3LMNA
SCHEMBL4293684 1.00 SLC28A1 (0.59) SLC28A1SLC28A2SLC29A1SLC28A3LMNA
SCHEMBL9293560 1.00 SLC28A1 (0.59) SLC28A1SLC28A2SLC29A1SLC28A3LMNA
SCHEMBL13657982 1.00 SLC28A1 (0.59) SLC28A1SLC28A2SLC29A1SLC28A3LMNA
SCHEMBL2115033 0.84 LMNA (0.62) SLC28A1SLC28A2SLC29A1SLC28A3LMNA
SCHEMBL21184966 0.84 LMNA (0.62) SLC28A1SLC28A2SLC29A1SLC28A3LMNA
SCHEMBL6676522 0.84 LMNA (0.62) SLC28A1SLC28A2SLC29A1SLC28A3LMNA
SCHEMBL16179302 0.80 SLC28A1 (0.59) SLC28A1SLC28A2SLC29A1SLC28A3LMNA
SCHEMBL7028245 0.79 MAPT (0.63) SLC28A1SLC28A2SLC29A1SLC28A3LMNA
SCHEMBL7028251 0.79 MAPT (0.63) SLC28A1SLC28A2SLC29A1SLC28A3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 615 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250268993-A1 ALKALINE PHOSPHATE-BASED ONCOLOGY TREATMENTS THERIVA BIOLOGICS, INC. 2025-08-28 US claimed
US-12318434-B2 Alkaline phosphate-based oncology treatments THERIVA BIOLOGICS, INC. (US) 2025-06-03 US claimed
EP-4470565-A1 METHOD FOR PREVENTING OR TREATING DISEASE OR DISORDER ASSOCIATED WITH ANTINEOPLASTIC AGENT OnQuality Pharmaceuticals China Ltd. (CN) 2024-12-04 EP claimed
CN-115998885-B Inhibitor combination and application thereof in preparation of medicines for treating MYC high-expression cancers 上海科技大学 2024-11-12 CN claimed
CN-118742325-A Methods for preventing or treating diseases or conditions associated with antineoplastic agents 上海岸阔医药科技有限公司 2024-10-01 CN claimed
EP-4238571-A1 APPLICATION OF THYMIDINE DERIVATIVE IN PREPARATION OF DRUGS OnQuality Pharmaceuticals China Ltd. (CN) 2023-09-06 EP claimed
WO-2023142996-A1 METHOD FOR PREVENTING OR TREATING DISEASE OR DISORDER ASSOCIATED WITH ANTINEOPLASTIC AGENT 上海岸阔医药科技有限公司 2023-08-03 WO claimed
CN-116437930-A Use of uridine derivatives in the preparation of medicaments 上海岸阔医药科技有限公司 2023-07-14 CN claimed
CN-116367842-A Application of thymidine derivative in preparing medicine 上海岸阔医药科技有限公司 2023-06-30 CN claimed
CN-115998885-A Inhibitor combination and application thereof in preparation of medicines for treating MYC high-expression cancers 上海科技大学 2023-04-25 CN claimed
EP-0594667-A1 TREATMENT OF CHEMOTHERAPEUTIC AGENT AND ANTIVIRAL AGENT TOXICITY WITH ACYLATED PYRIMIDINE NUCLEOSIDES PRO-NEURON, INC. (US) 1994-05-04 EP claimed
EP-0577725-A1 TARGETED DRUG DELIVERY VIA MIXED PHOSPHATE DERIVATIVES UNIVERSITY OF FLORIDA (US) 1994-01-12 EP claimed
EP-0539493-A4 TARGETED DRUG DELIVERY VIA PHOSPHONATE DERIVATIVES 1993-06-02 EP claimed
EP-0539493-A1 TARGETED DRUG DELIVERY VIA PHOSPHONATE DERIVATIVES. BODOR NICHOLAS S (US) 1993-05-05 EP claimed
WO-1993001202-A1 TREATMENT OF CHEMOTHERAPEUTIC AGENT AND ANTIVIRAL AGENT TOXICITY WITH ACYLATED PYRIMIDINE NUCLEOSIDES PRO-NEURON, INC. (US) 1993-01-21 WO claimed
US-5177064-A TARGETED DRUG DELIVERY VIA PHOSPHONATE DERIVATIVES UNIVERSITY OF FLORIDA (US) 1993-01-05 US claimed
EP-0359347-B1 COVALENTLY-LINKED COMPLEXES AND METHODS FOR ENHANCED CYTOTOXICITY AND IMAGING NEORX CORPORATION (US) 1992-12-23 EP claimed
WO-1992017185-A1 TARGETED DRUG DELIVERY VIA MIXED PHOSPHATE DERIVATIVES UNIVERSITY OF FLORIDA (US) 1992-10-15 WO claimed
WO-1992000988-A1 TARGETED DRUG DELIVERY VIA PHOSPHONATE DERIVATIVES BODOR NICHOLAS S (US) 1992-01-23 WO claimed
EP-0359347-A2 Covalently-linked complexes and methods for enhanced cytotoxicity and imaging NEORX CORPORATION (US) 1990-03-21 EP claimed