SCHEMBL353141

SCHEMBL353141

O=C(O)c1cccnc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 1.00
LMNA P02545 1/20 1.00
KDM4E B2RXH2 2/20 0.63
TDP1 Q9NUW8 1/20 0.63
ALDH1A1 P00352 3/20 0.61
L3MBTL1 Q9Y468 2/20 0.61
ALOX15 P16050 2/20 0.61
CYP3A4 P08684 1/20 0.61
MAPT P10636 1/20 0.61
TSHR P16473 1/20 0.61
BLM P54132 1/20 0.61
AGER Q15109 1/20 0.61
NPSR1 Q6W5P4 1/20 0.61
NAPRT Q6XQN6 2/20 0.59
POLB P06746 1/20 0.56
DHODH Q02127 2/20 0.53
MEN1 O00255 1/20 0.53
RAB9A P51151 1/20 0.53
KMT2A Q03164 1/20 0.53
CYP1A2 P05177 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29412848 1.00 SMN1; SMN2 (1.00) SMN1; SMN2LMNAKDM4ETDP1ALDH1A1
SCHEMBL30792459 1.00 SMN1; SMN2 (1.00) SMN1; SMN2LMNAKDM4ETDP1ALDH1A1
Hydrochloric Acid SCHEMBL587011 0.98 SMN1; SMN2 (0.96) SMN1; SMN2LMNAKDM4ETDP1ALDH1A1
SCHEMBL28965993 0.98 SMN1; SMN2 (0.96) SMN1; SMN2LMNAKDM4ETDP1ALDH1A1
SCHEMBL28965992 0.98 SMN1; SMN2 (0.96) SMN1; SMN2LMNAKDM4ETDP1ALDH1A1
SCHEMBL5250407 0.98 SMN1; SMN2 (0.96) SMN1; SMN2LMNAKDM4ETDP1ALDH1A1
SCHEMBL31572603 0.98 SMN1; SMN2 (0.96) SMN1; SMN2LMNAKDM4ETDP1ALDH1A1
Ammonia Solution, Strong SCHEMBL28484422 0.98 SMN1; SMN2 (0.96) SMN1; SMN2LMNAKDM4ETDP1ALDH1A1
Ethane SCHEMBL3957942 0.96 SMN1; SMN2 (0.92) SMN1; SMN2LMNAKDM4ETDP1ALDH1A1
Dimethylamine SCHEMBL31596353 0.92 SMN1; SMN2 (0.85) SMN1; SMN2LMNAKDM4ETDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3339 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12516359-B2 Nitrilase mutant and use thereof in catalytic synthesis of 2-chloronicotinic acid ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) 2026-01-06 US claimed
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
US-12497636-B2 Recombinant Saccharomyces cerevisiae cells for cannabinoid production NATIONAL UNIVERSITY OF SINGAPORE (SG) 2025-12-16 US claimed
CN-115710217-B Flunixin meglumine synthesis method suitable for industrial production 江苏恒盛药业有限公司 2025-06-13 CN claimed
CN-120136886-A PDE4 inhibitor with pyranonaphthyridone skeleton and preparation method and application thereof 中山大学 2025-06-13 CN claimed
CN-120058601-A Preparation process of nicosulfuron intermediate 2-chloro-N, N-dimethyl nicotinamide 河北临港化工有限公司 2025-05-30 CN claimed
CN-118812551-B Synthesis preparation process of pranoprofen 盐城凯利药业有限公司 2025-05-30 CN claimed
CN-119426165-B Vibrating screen for screening 2-chloronicotinic acid 沧州临港亚诺化工有限公司 2025-05-16 CN claimed
CN-119955119-A Luminous lead coordination polymer and preparation method thereof 池州学院 2025-05-09 CN claimed
CN-222841829-U Separation purifier 老河口市天和科技有限公司 2025-05-09 CN claimed
US-4987232-A ONE POT, GOOD YIELD SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ, B.V. (NL) 1991-01-22 US claimed
EP-0372654-A2 Preparation of 2-chloropyridine 3-carboxylic acid esters SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1990-06-13 EP claimed
EP-0349902-A2 Processes for the preparation of morniflumate and analogous compounds CHIESI FARMACEUTICI S.p.A. (IT) 1990-01-10 EP claimed
US-4841046-A Process for the preparation of pyridobenzodiazepinone DOMPE' FARMACEUTICI S.P.A. (IT) 1989-06-20 US claimed
EP-0314163-A2 Process for the preparation of 6,11-dihydro-5H-pyrido(2,3-b)(1,5)benzodiazepin-5-one DOMPE' FARMACEUTICI S.p.A. (IT) 1989-05-03 EP claimed
EP-0092117-B1 PROCESS FOR PRODUCING CHLORONICOTINIC ACID COMPOUNDS ISHIHARA SANGYO KAISHA, LTD. (JP) 1987-07-15 EP claimed
US-4504665-A Process for producing chloronicotinic acid compounds ISHIHARA SANGYO KAISHA LTD. (JP) 1985-03-12 US claimed
EP-0092117-A1 Process for producing chloronicotinic acid compounds ISHIHARA SANGYO KAISHA, LTD. (JP) 1983-10-26 EP claimed
EP-0024172-B1 ANTITUMOR AND IMMUNOSUPPRESSIVE 4-CARBAMOYLIMIDAZOLIUM-5-OLATE DERIVATIVES, PHARMACEUTICAL COMPOSITION AND PRODUCTION THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-05-11 EP claimed
US-4144238-A Process for the production of pure white 2-chloronicotinic acid LONZA, LTD. (CH) 1979-03-13 US claimed