Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR known ✓ | P00533 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.96 |
| ▸ | LMNA | P02545 | 1/20 | 0.96 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | AGER | Q15109 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | DHODH | Q02127 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL353141 | 0.98 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNAKDM4ETDP1L3MBTL1 | |
| SCHEMBL30792459 | 0.98 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNAKDM4ETDP1L3MBTL1 | |
| SCHEMBL29412848 | 0.98 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNAKDM4ETDP1L3MBTL1 | |
| SCHEMBL5250407 | 0.96 | SMN1; SMN2 (0.96) | SMN1; SMN2LMNAKDM4ETDP1L3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL28484422 | 0.96 | SMN1; SMN2 (0.96) | SMN1; SMN2LMNAKDM4ETDP1L3MBTL1 | |
| SCHEMBL28965992 | 0.96 | SMN1; SMN2 (0.96) | SMN1; SMN2LMNAKDM4ETDP1L3MBTL1 | |
| SCHEMBL28965993 | 0.96 | SMN1; SMN2 (0.96) | SMN1; SMN2LMNAKDM4ETDP1L3MBTL1 | |
| SCHEMBL31572603 | 0.96 | SMN1; SMN2 (0.96) | SMN1; SMN2LMNAKDM4ETDP1L3MBTL1 | |
| Ethane SCHEMBL3957942 | 0.94 | SMN1; SMN2 (0.92) | SMN1; SMN2LMNAKDM4ETDP1L3MBTL1 | |
| Dimethylamine SCHEMBL31596353 | 0.90 | SMN1; SMN2 (0.85) | SMN1; SMN2LMNAKDM4ETDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144238-A | Process for the production of pure white 2-chloronicotinic acid | LONZA, LTD. (CH) | 1979-03-13 | — | — | US | claimed |
| US-4080336-A | Process for the production of 2-chloronicotinic acid amide | LONZA LTD. (CH) | 1978-03-21 | — | — | US | claimed |
| US-20250263379-A1 | NOVEL PYRIDINIUM COMPOUND | KAO CORPORATION (JP) | 2025-08-21 | — | — | US | disclosed |
| US-20250250514-A1 | COMPOSITION | KAO CORPORATION (JP) | 2025-08-07 | — | — | US | disclosed |
| EP-4509486-A1 | COMPOSITION | Kao Corporation (JP) | 2025-02-19 | — | — | EP | disclosed |
| EP-4509495-A1 | NOVEL PYRIDINIUM COMPOUND | Kao Corporation (JP) | 2025-02-19 | — | — | EP | disclosed |
| WO-2023199939-A1 | COMPOSITION | 花王株式会社 | 2023-10-19 | — | — | WO | disclosed |
| WO-2023199938-A1 | NOVEL PYRIDINIUM COMPOUND | 花王株式会社 | 2023-10-19 | — | — | WO | disclosed |
| EP-3081552-B1 | PEST CONTROL AGENT CONTAINING AN AMIDE DERIVATIVE AND USE OF THE PEST CONTROL AGENT | MITSUI CHEMICALS AGRO INC (JP) | 2021-03-03 | — | — | EP | disclosed |
| EP-3564217-B1 | P2X4 RECEPTOR ANTAGONIST | NIPPON CHEMIPHAR CO (JP) | 2021-01-27 | — | — | EP | disclosed |
| US-10582708-B2 | Amide derivative, pest control agent containing the amide derivative, and use of the amide derivative | MITSUI CHEMICALS AGRO, INC. (JP) | 2020-03-10 | — | — | US | disclosed |
| EP-0092117-B1 | PROCESS FOR PRODUCING CHLORONICOTINIC ACID COMPOUNDS | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1987-07-15 | — | — | EP | disclosed |
| US-4504665-A | Process for producing chloronicotinic acid compounds | ISHIHARA SANGYO KAISHA LTD. (JP) | 1985-03-12 | — | — | US | disclosed |
| EP-0092117-A1 | Process for producing chloronicotinic acid compounds | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1983-10-26 | — | — | EP | disclosed |
| US-4284629-A | ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-18 | — | — | US | disclosed |
| US-4144238-A | Process for the production of pure white 2-chloronicotinic acid | LONZA, LTD. (CH) | 1979-03-13 | — | — | US | disclosed |
| US-4144238-A | Process for the production of pure white 2-chloronicotinic acid | LONZA, LTD. (CH) | 1979-03-13 | — | — | US | disclosed |
| US-4080336-A | Process for the production of 2-chloronicotinic acid amide | LONZA LTD. (CH) | 1978-03-21 | — | — | US | disclosed |
| US-4080336-A | Process for the production of 2-chloronicotinic acid amide | LONZA LTD. (CH) | 1978-03-21 | — | — | US | disclosed |
| US-4072680-A | Derivatives of pyrazolo[1,5-a]pyrido[3,2-e]pyrimidine | E. R. SQUIBB & SONS, INC. (US) | 1978-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10582708-B2 | Amide derivative, pest control agent containing the amide derivative, and use of the amide derivative | H1-2, H1-4, H1-0 | EGFR 4176/4885SMN1; SMN2 4436/4885LMNA 2595/4885 |
| US-20250263379-A1 | NOVEL PYRIDINIUM COMPOUND | PYM1, F11, CHRM1 | EGFR 2823/4885SMN1; SMN2 2077/4885LMNA 2043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.