P-Nitrophenylphosphate

P-Nitrophenylphosphate

SCHEMBL35320

O=[N+]([O-])c1ccc(OP(=O)(O)O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 1.00
CA2 P00918 3/20 1.00
CES1 P23141 2/20 0.79
CES2 O00748 1/20 0.79
BCHE P06276 1/20 0.57
ACHE P22303 1/20 0.57
MAPK1 P28482 3/20 0.56
ALDH1A1 P00352 2/20 0.56
CYP3A4 P08684 2/20 0.56
HSD17B10 Q99714 2/20 0.56
LMNA P02545 1/20 0.56
TP53 P04637 1/20 0.56
THRB P10828 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
SRC P12931 1/20 0.52
AKR1C3 P42330 1/20 0.51
TSHR P16473 1/20 0.51
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
HSPB1 P04792 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Nitrophenylphosphate SCHEMBL28027358 1.00 CA1 (1.00) CA1CA2CES1CES2BCHE
P-Nitrophenylphosphate SCHEMBL28396311 0.98 CA1 (0.96) CA1CA2CES1CES2BCHE
P-Nitrophenylphosphate SCHEMBL11322616 0.98 CA1 (0.96) CA1CA2CES1CES2BCHE
P-Nitrophenylphosphate SCHEMBL4744271 0.98 CA1 (0.96) CA1CA2CES1CES2BCHE
P-Nitrophenylphosphate SCHEMBL3095493 0.98 CA1 (0.96) CA1CA2CES1CES2BCHE
P-Nitrophenylphosphate SCHEMBL3211717 0.98 CA1 (0.96) CA1CA2CES1CES2BCHE
P-Nitrophenylphosphate SCHEMBL11322606 0.98 CA1 (0.96) CA1CA2CES1CES2BCHE
P-Nitrophenylphosphate SCHEMBL11152111 0.98 CA1 (0.96) CA1CA2CES1CES2BCHE
P-Nitrophenylphosphate SCHEMBL3097581 0.98 CA1 (0.96) CA1CA2CES1CES2BCHE
P-Nitrophenylphosphate SCHEMBL8381854 0.98 CA1 (0.96) CA1CA2CES1CES2BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 39320 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026085618-A1 METHOD OF IMMOBILIZING CAPTURE PROBES TO SOLID PHASES FOR TARGET SUBSTANCE DETECTION YYZ PHARMATECH INC. (CA) 2026-04-30 WO claimed
US-12545945-B2 Methods for detection of rare subpopulations of cells and highly purified composition of cells ASTELLAS INSTITUTE FOR REGENERATIVE MEDICINE (US) 2026-02-10 US claimed
US-20260036584-A1 COMPOSITIONS AND METHODS TO DETECT GASTROINTESTINAL DISEASE THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIV AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2026-02-05 US claimed
EP-4189339-B1 WIDEBAND BACK-ILLUMINATED ELECTROMAGNETIC RADIATION DETECTORS APPLE INC (US) 2026-01-28 EP claimed
EP-4677353-A1 SYSTEM FOR LABEL-FREE ELECTROCHEMICAL SENSING President And Fellows Of Harvard College (US) 2026-01-14 EP claimed
US-20250383362-A1 MASS SPECTROMETRIC ANALYSIS OF BIOMARKERS IDEXX LABORATORIES, INC. (US) 2025-12-18 US claimed
US-20250354204-A1 AUTOMATED RNA DETECTION USING LABELED 2'-O-METHYL RNA OLIGONUCLEOTIDE PROBES AND SIGNAL AMPLIFICATION SYSTEMS VENTANA MED SYST INC (US) 2025-11-20 US claimed
EP-4637776-A1 USE OF DUPD1 INHIBITORS IN THE TREATMENT OF INFLAMMATORY BOWEL DISEASE AND METABOLIC DISORDERS The Governing Council of the University of Toronto (CA) 2025-10-29 EP claimed
US-12398205-B2 Anti-interferon gamma antibodies and uses thereof Elixiron Immunotherapeutics (hong Kong) Limited (CN) 2025-08-26 US claimed
EP-4452489-B1 CATALYST COMPOSITION FOR OLIGOMERIZATION REACTION SABIC GLOBAL TECHNOLOGIES BV (NL) 2025-07-23 EP claimed
US-4474878-A IMMUNOASSAY, ANTIBODIES CORDIS LABORATORIES, INC. (US) 1984-10-02 US claimed
EP-0106370-A2 Specific binding assays utilizing analyte-cytolysin conjugates E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-04-25 EP claimed
US-4406751-A INCUBATION, NITROAROMATIC PHOSPHATE ESTER BLASS KARL G 1983-09-27 US claimed
EP-0085348-A1 Reagents for the determination of enzymes AMERICAN HOECHST CORPORATION (US) 1983-08-10 EP claimed
US-4372874-A Stabilization of hydrolysis prone labile organic reagents in liquid media MEDICAL ANALYSIS SYSTEMS, INC. 1983-02-08 US claimed
US-4306020-A Composition for the analysis of the alkaline phosphatase and method therefor ISTITUTO SIEROTERAPICO E VACCINOGENO TOSCANO "SCLAVO" S.P.A. (IT) 1981-12-15 US claimed
EP-0006582-A2 Method for stabilizing solutions of gamma-glutamyl-p-nitroanilide Modrovich, Ivan Endre (US) 1980-01-09 EP claimed
US-4162194-A DEETHERIFICATION, PHOSPHORYLATION AND TRANSPHOSPHORYLATION BECKMAN INSTRUMENTS, INC. (US) 1979-07-24 US claimed
US-4157280-A Test set for detecting the presence of antigens associated with hepatitis CORDIS CORPORATION (US) 1979-06-05 US claimed
US-4129417-A Multisystem test means MILES LABORATORIES, INC. (US) 1978-12-12 US claimed