Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 19/20 | 0.61 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL3294614 | 0.97 | P2RX7 (0.58) | P2RX7 | |
| SCHEMBL3531141 | 0.93 | P2RX7 (0.52) | P2RX7SCN2ASCN10A | |
| SCHEMBL3537861 | 0.89 | P2RX7 (0.76) | P2RX7 | |
| SCHEMBL3528235 | 0.88 | P2RX7 (0.49) | P2RX7 | |
| SCHEMBL3288189 | 0.86 | P2RX7 (0.47) | P2RX7 | |
| SCHEMBL3535328 | 0.86 | P2RX7 (0.47) | P2RX7 | |
| SCHEMBL3530880 | 0.86 | P2RX7 (0.47) | P2RX7 | |
| SCHEMBL3532824 | 0.86 | P2RX7 (0.47) | P2RX7 | |
| SCHEMBL3529676 | 0.86 | P2RX7 (0.47) | P2RX7 | |
| SCHEMBL3534759 | 0.86 | P2RX7 (0.71) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7704997-B1 | Amino-tetrazole analogues and methods of use | ABBOTT LABORATORIES (US) | 2010-04-27 | — | — | US | claimed |