⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL92737 | 1.00 | — | — | |
| SCHEMBL239908 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL1372569 | 0.97 | — | — | |
| Ammonia Solution, Strong SCHEMBL22437494 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL1372999 | 0.97 | — | — | |
| SCHEMBL7027341 | 0.97 | — | — | |
| SCHEMBL7016182 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL22418822 | 0.97 | NOS2 (0.48) | — | |
| SCHEMBL7016184 | 0.97 | — | — | |
| SCHEMBL6677658 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1037 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304564-B | Preparation method of S-tetrahydrofuranic acid | 成都融创亿恒生物医药科技有限公司 | 2024-09-24 | — | — | CN | claimed |
| US-11939314-B2 | Quinolin-2-one derivatives | MERCK PATENT GMBH (DE) | 2024-03-26 | — | — | US | claimed |
| CN-114014874-B | Preparation method of Mabalo Sha Wei intermediate | 中国科学院上海药物研究所 | 2023-04-28 | — | — | CN | claimed |
| US-20230028687-A1 | QUINOLIN-2-ONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2023-01-26 | — | — | US | claimed |
| CN-115304564-A | Preparation method of S-tetrahydrofuran formic acid | 成都融创亿恒生物医药科技有限公司 | 2022-11-08 | — | — | CN | claimed |
| CN-110105372-B | Preparation method of R-7- (benzyloxy) -tetrahydro-1H-oxazine pyrido-triazine-6, 8-diketone | 南京焕然生物科技有限公司 | 2022-05-10 | — | — | CN | claimed |
| US-11299484-B2 | Inhibiting fatty acid synthase (FASN) | FORMA THERAPEUTICS, INC. (US) | 2022-04-12 | — | — | US | claimed |
| US-11174241-B2 | Quinolin-2-one derivatives | MERCK PATENT GMBH (DE) | 2021-11-16 | — | — | US | claimed |
| CN-108473485-B | Quinolin-2-one derivatives | 默克专利股份公司 | 2021-11-02 | — | — | CN | claimed |
| US-20210024508-A1 | INHIBITING FATTY ACID SYNTHASE (FASN) | FORMA THERAPEUTICS, INC. | 2021-01-28 | — | — | US | claimed |
| WO-2005000842-A1 | BENZOTHIAZOLE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | F. HOFFMAN-LA ROCHE AG (CH) | 2005-01-06 | — | — | WO | claimed |
| US-20040235915-A1 | Benzothiazole derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2004-11-25 | — | — | US | claimed |
| US-20040229863-A1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2004-11-18 | — | — | US | claimed |
| US-20030114437-A1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-06-19 | — | — | US | claimed |
| EP-1278502-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2003-05-21 | — | — | EP | claimed |
| EP-1278502-A2 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2003-01-29 | — | — | EP | claimed |
| WO-2001089451-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-29 | — | — | WO | claimed |
| EP-0536329-B1 | R(+)-TERAZOSIN | ABBOTT LAB (US) | 1996-04-17 | — | — | EP | claimed |
| EP-0464058-B1 | FERROELECTRIC LIQUID CRYSTAL MIXTURES | HOECHST AG (DE) | 1995-06-14 | — | — | EP | claimed |
| US-5378394-A | Pyrimidine compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-01-03 | — | — | US | claimed |