⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717786 | 0.64 | — | — | |
| SCHEMBL5858946 | 0.57 | — | — | |
| SCHEMBL7338780 | 0.57 | ALDH1A1 (0.33) | — | |
| SCHEMBL225030 | 0.57 | ALDH1A1 (0.33) | — | |
| SCHEMBL7684525 | 0.57 | — | — | |
| SCHEMBL9717677 | 0.55 | — | — | |
| SCHEMBL10530399 | 0.55 | — | — | |
| SCHEMBL11881649 | 0.54 | CRBN (0.34) | — | |
| SCHEMBL9743198 | 0.52 | — | — | |
| SCHEMBL1506467 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9199940-B2 | Crystalline forms and processes for the preparation of phenyl-pyrazoles useful as modulators of the 5-HT2A serotonin receptor | ARENA PHARMACEUTICALS, INC. (US) | 2015-12-01 | — | — | US | disclosed |
| US-9102627-B2 | Processes for preparing 3-benzazepines | ARENA PHARMACEUTICALS, INC. | 2015-08-11 | — | — | US | disclosed |
| US-20130296321-A1 | CRYSTALLINE FORMS AND PROCESSES FOR THE PREPARATION OF PHENYL-PYRAZOLES USEFUL AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR | ARENA PHARMACEUTICALS, INC. | 2013-11-07 | — | — | US | disclosed |
| US-8481535-B2 | Crystalline forms and processes for the preparation of phenyl-pyrazoles useful as modulators of the 5-HT2A serotonin receptor | ARENA PHARMACEUTICALS, INC. (US) | 2013-07-09 | — | — | US | disclosed |
| US-20130165648-A1 | PROCESSES FOR PREPARING 3-BENZAZEPINES | ARENA PHARMACEUTICALS, INC. | 2013-06-27 | — | — | US | disclosed |
| US-8415340-B2 | Triazine kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-04-09 | — | — | US | disclosed |
| US-8343999-B2 | Thiazolyl compounds useful as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-01-01 | — | — | US | disclosed |
| US-8293919-B2 | Antibacterial sulfone and sulfoxide substituted heterocyclic urea compounds | CRESTONE, INC. (US) | 2012-10-23 | — | — | US | disclosed |
| US-8273772-B2 | Heteroaryl compounds as P2Y1 receptor inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-09-25 | — | — | US | disclosed |
| US-8268826-B2 | 5-({4-[(3S)-4-(5-bromo-2,3-dihydro-1H-inden-1-yl)-3-methylpiperazin-1-yl]-4-methylpiperidin-1-yl}carbonyl)-4,6-dimethylpyrimidine; inflammatory diseases, immune diseases and viral infections; HIV | INCYTE CORPORATION (US) | 2012-09-18 | — | — | US | disclosed |
| US-20080207898-A1 | PROCESSES FOR THE PREPARATION OF AMINOETHOXYBENZYL ALCOHOLS | WYETH (US) | 2008-08-28 | — | — | US | disclosed |
| US-20080194836-A1 | Process for Preparing Substituted Phenylpyrazole Ureas | ARENA PHARMACEUTICALS, INC. | 2008-08-14 | — | — | US | disclosed |
| US-7388021-B2 | Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions | BRISTOL MYERS SQUIBB COMPANY (US) | 2008-06-17 | — | — | US | disclosed |
| US-20080108586-A1 | COMBINATION THERAPY FOR HUMAN IMMUNODEFICIENCY VIRUS INFECTION | INCYTE CORPORATION (US) | 2008-05-08 | — | — | US | disclosed |
| US-20080004263-A1 | Ligands of Follicle Stimulating Hormone Receptor and Methods of Use Thereof | ARENA PHARMACEUTICALS, INC. | 2008-01-03 | — | — | US | disclosed |
| US-20070208054-A1 | MACROCYCLIC FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY | 2007-09-06 | — | — | US | disclosed |
| US-20060211720-A1 | Heterocyclic compounds as inhibitors of factor VIIa | BRISTOL-MYERS SQUIBB COMPANY | 2006-09-21 | — | — | US | disclosed |
| US-20060166997-A1 | Phenylglycinamide derivatives useful as anticoagulants | BRISTOL-MYERS SQUIBB COMPANY | 2006-07-27 | — | — | US | disclosed |
| US-20050267119-A1 | Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions | BRISTOL-MYERS SQUIBB COMPANY | 2005-12-01 | — | — | US | disclosed |
| US-20050261310-A1 | Piperazinylpiperidine derivatives as chemokine receptor antagonists | INCYTE CORPORATION | 2005-11-24 | — | — | US | disclosed |