Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 5/20 | 0.38 |
| ▸ | NOS3 | P29474 | 3/20 | 0.38 |
| ▸ | BACE1 | P56817 | 5/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | NOS1 | P29475 | 4/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5466523 | 0.84 | KCNH2 (0.39) | NOS2BACE1NOS1KCNH2IRAK4 | |
| SCHEMBL929267 | 0.83 | KCNH2 (0.38) | NOS2BACE1NOS1KCNH2IRAK4 | |
| SCHEMBL20436590 | 0.81 | KCNH2 (0.39) | BACE1KCNH2IRAK4 | |
| SCHEMBL28521511 | 0.81 | IRAK4 (0.36) | BACE1KCNH2IRAK4 | |
| SCHEMBL20416847 | 0.81 | KCNH2 (0.39) | BACE1KCNH2IRAK4 | |
| SCHEMBL15968790 | 0.81 | MEN1 (0.39) | NOS2NOS3BACE1KCNH2IRAK4 | |
| SCHEMBL30505267 | 0.81 | MEN1 (0.39) | NOS2NOS3BACE1KCNH2IRAK4 | |
| SCHEMBL23355664 | 0.80 | IRAK4 (0.33) | BACE1KCNH2IRAK4 | |
| SCHEMBL4712759 | 0.80 | HRH1 (0.37) | NOS2BACE1NOS1KCNH2IRAK4 | |
| SCHEMBL4715736 | 0.79 | KCNH2 (0.38) | BACE1KCNH2IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111655677-B | Benzimidazole compounds as agrochemicals | 瑞戴格作物保护公司 | 2024-05-03 | — | — | CN | disclosed |
| EP-4310082-A2 | AZOLOPYRIMIDINE FOR THE TREATMENT OF CANCER-RELATED DISORDERS | Arcus Biosciences, Inc. (US) | 2024-01-24 | — | — | EP | disclosed |
| EP-3570844-B1 | AZOLOPYRIMIDINE FOR THE TREATMENT OF CANCER-RELATED DISORDERS | ARCUS BIOSCIENCES INC (US) | 2023-09-06 | — | — | EP | disclosed |
| US-11641858-B2 | Agricultural chemicals | REDAG CROP PROTECTION LTD. (GB) | 2023-05-09 | — | — | US | disclosed |
| US-11641858-B2 | Agricultural chemicals | REDAG CROP PROTECTION LTD. (GB) | 2023-05-09 | — | — | US | disclosed |
| US-11641858-B2 | Agricultural chemicals | REDAG CROP PROTECTION LTD. (GB) | 2023-05-09 | — | — | US | disclosed |
| US-20220144808-A1 | AZOLOPYRIMIDINE FOR THE TREATMENT OF CANCER-RELATED DISORDERS | ARCUS BIOSCIENCES, INC. | 2022-05-12 | — | — | US | disclosed |
| CN-109071495-B | Agricultural chemicals | 瑞戴格作物保护公司 | 2022-04-19 | — | — | CN | disclosed |
| EP-3697771-B1 | BENZIMIDAZOLE COMPOUNDS AS AGRICULTURAL CHEMICALS | REDAG CROP PROT LTD (GB) | 2022-04-06 | — | — | EP | disclosed |
| US-11241013-B2 | Benzimidazole compounds as agricultural chemicals | REDAG CROP PROT LTD (GB) | 2022-02-08 | — | — | US | disclosed |
| US-20060106029-A1 | Novel aminopyridine derivatives having aurora a selective inhibitory action | MSD K.K. (JP) | 2006-05-18 | — | — | US | disclosed |
| WO-2006040526-A1 | QUINAZOLINE DERIVATIVES FOR USE AGAINST CANCER | ASTRAZENECA AB (SE) | 2006-04-20 | — | — | WO | disclosed |
| EP-1218376-B1 | TYROSINE KINASE INHIBITORS | MERCK & CO INC (US) | 2005-11-09 | — | — | EP | disclosed |
| US-6586424-B2 | Anticancer agents; anticholesterol agents | MERCK & CO., INC. | 2003-07-01 | — | — | US | disclosed |
| US-6586423-B2 | 2-(Pyridin-2-ylamino)-thiazole-5-carbonitrile derivatives; angiogenesis inhibitors; antitumor and anticarcinogenic agents; atherosclerosis, macular degeneration, diabetic retinopathy | MERCK & CO., INC. | 2003-07-01 | — | — | US | disclosed |
| US-20030064996-A1 | Tyrosine kinase inhibitors | MERCK SHARP & DOHME CORP. | 2003-04-03 | — | — | US | disclosed |
| EP-1218376-A4 | TYROSINE KINASE INHIBITORS | MERCK & CO INC (US) | 2002-11-20 | — | — | EP | disclosed |
| US-20020147203-A1 | Tyrosine kinase inhibitors | MERCK & CO., INC. | 2002-10-10 | — | — | US | disclosed |
| EP-1218376-A1 | TYROSINE KINASE INHIBITORS | Merck & Co., Inc. (US) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001017995-A1 | TYROSINE KINASE INHIBITORS | MERCK & CO., INC. (US) | 2001-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147203-A1 | Tyrosine kinase inhibitors | ERBB2, TYRO3, TIE1 | NOS2 895/4885NOS3 718/4885BACE1 2477/4885 |
| US-20220144808-A1 | AZOLOPYRIMIDINE FOR THE TREATMENT OF CANCER-RELATED DISORDERS | ADORA2A, ADORA2B, ADORA1 | NOS2 3024/4885NOS3 4021/4885BACE1 4667/4885 |
| US-20030064996-A1 | Tyrosine kinase inhibitors | ERBB2, TYRO3, TIE1 | NOS2 895/4885NOS3 718/4885BACE1 2477/4885 |
| US-11241013-B2 | Benzimidazole compounds as agricultural chemicals | CYP3A4, CYP2C8, CYP2E1 | NOS2 2119/4885NOS3 1730/4885BACE1 3075/4885 |
| US-20060106029-A1 | Novel aminopyridine derivatives having aurora a selective inhibitory action | AURKA, AURKC, AURKB | NOS2 2426/4885NOS3 1864/4885BACE1 3316/4885 |
| US-11641858-B2 | Agricultural chemicals | DDT, CYP4X1, CYP1A2 | NOS2 381/4885NOS3 205/4885BACE1 1620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.