⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4789987 | 0.73 | — | — | |
| SCHEMBL3540181 | 0.73 | — | — | |
| SCHEMBL16965015 | 0.60 | — | — | |
| SCHEMBL1128850 | 0.60 | — | — | |
| SCHEMBL2323525 | 0.56 | — | — | |
| SCHEMBL1129054 | 0.49 | — | — | |
| Ammonia Solution, Strong SCHEMBL28776475 | 0.33 | — | — | |
| Calcium Bromide SCHEMBL20474462 | 0.32 | — | — | |
| SCHEMBL11304345 | 0.32 | — | — | |
| Calcium Bromide SCHEMBL21045711 | 0.30 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957496-B1 | BICYCLIC PROTEIN KINASE INHIBITORS | OSI PHARM INC (US) | 2012-10-24 | — | — | EP | disclosed |
| US-7648987-B2 | Bicyclic protein kinase inhibitors | OSI PHARMACEUTICALS, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| US-20070149521-A1 | Bicyclic protein kinase inhibitors | OSI PHARMACEUTICALS, INC. | 2007-06-28 | — | — | US | disclosed |