⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3535322 | 0.73 | — | — | |
| SCHEMBL3540181 | 0.73 | — | — | |
| SCHEMBL1129371 | 0.59 | — | — | |
| SCHEMBL1129068 | 0.59 | — | — | |
| SCHEMBL2323525 | 0.56 | — | — | |
| Ammonia Solution, Strong SCHEMBL28776475 | 0.33 | — | — | |
| Calcium Bromide SCHEMBL20474462 | 0.32 | — | — | |
| Ammonia Solution, Strong SCHEMBL8666268 | 0.28 | — | — | |
| Ammonia Solution, Strong SCHEMBL5202407 | 0.28 | — | — | |
| Ammonia Solution, Strong SCHEMBL28164637 | 0.28 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957496-A2 | BICYCLIC PROTEIN KINASE INHIBITORS | OSI Pharmaceuticals, Inc. (US) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007064993-A2 | BICYCLIC PROTEIN KINASE INHIBITORS | OSI PHARMACEUTICALS, INC. (US) | 2007-06-07 | — | — | WO | disclosed |