⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11146460 | 0.98 | CRBN (0.95) | — | |
| SCHEMBL28561591 | 0.89 | CRBN (0.80) | — | |
| SCHEMBL28306486 | 0.80 | CRBN (0.65) | — | |
| SCHEMBL15794740 | 0.80 | CRBN (0.65) | — | |
| SCHEMBL6560863 | 0.79 | CRBN (0.62) | — | |
| SCHEMBL6456192 | 0.78 | CRBN (0.61) | — | |
| SCHEMBL16576197 | 0.76 | — | — | |
| SCHEMBL20879444 | 0.76 | — | — | |
| SCHEMBL297037 | 0.76 | — | — | |
| SCHEMBL28426470 | 0.74 | CRBN (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3578 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026099316-A1 | COMPOUNDS AND METHODS FOR REDUCING ARHGEF6 EXPRESSION | ASTRAZENECA AB (SE) | 2026-05-15 | — | — | WO | claimed |
| US-12605400-B2 | Oligomeric nucleic acid molecule, and application thereof in an acute intermittent porphyria treatment | RACTIGEN THERAPEUTICS (CN) | 2026-04-21 | — | — | US | claimed |
| EP-4720297-A2 | OPA1 ANTISENSE OLIGOMERS FOR TREATMENT OF CONDITIONS AND DISEASES | Stoke Therapeutics, Inc. (US) | 2026-04-08 | — | — | EP | claimed |
| EP-4677085-A1 | OLIGONUCLEOTIDE MODULATORS ACTIVATING FACTOR VII EXPRESSION AND USE THEREOF IN TREATMENT OF HEMOPHILIA | Ractigen Therapeutics (CN) | 2026-01-14 | — | — | EP | claimed |
| US-20250346624-A1 | POLYNUCLEOTIDE AND PRODUCING METHOD THEREOF | EISAI R&D MAN CO LTD (JP) | 2025-11-13 | — | — | US | claimed |
| WO-2025201529-A1 | COMPOUNDS FOR SYNTHESIZING MODIFIED SMALL ACTIVATING RNA MOLECULES, MODIFIED SMALL ACTIVATING RNA MOLECULES AND USES THEREOF | RACTIGEN THERAPEUTICS (CN) | 2025-10-02 | — | — | WO | claimed |
| EP-4617375-A2 | METHODS, COMPOSITIONS AND SYSTEMS FOR IMPROVING THE BINDING OF METHYLATED POLYNUCLEOTIDES | Guardant Health, Inc. (US) | 2025-09-17 | — | — | EP | claimed |
| CN-120158489-A | Cyclic RNA precursor, method for producing same, and cyclic RNA obtained thereby | 上海兆维医药科技有限公司 | 2025-06-17 | — | — | CN | claimed |
| CN-120054582-A | Mono-atom catalyst for denitration and sulfur resistance and preparation method thereof | 福州大学 | 2025-05-30 | — | — | CN | claimed |
| EP-4065725-B1 | METHODS, COMPOSITIONS AND SYSTEMS FOR IMPROVING THE BINDING OF METHYLATED POLYNUCLEOTIDES | GUARDANT HEALTH INC (US) | 2025-05-21 | — | — | EP | claimed |
| WO-1994022449-A1 | THERAPEUTIC COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-10-13 | — | — | WO | claimed |
| WO-1994022863-A1 | SECOND MESSENGER CELL SIGNALING INHIBITORS | CELL THERAPEUTICS, INC. (US) | 1994-10-13 | — | — | WO | claimed |
| WO-1994015606-A1 | OLEFIN-SUBSTITUTED LONG CHAIN COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-07-21 | — | — | WO | claimed |
| CN-1013076-B | PROCESS FOR PREPARING HETEROCYCLIC COMPOUNDS | HOFFMANN LA ROCHE (CH) | 1991-07-10 | — | — | CN | claimed |
| EP-0174879-B1 | POLYNUCLEOTIDES COVALENTLY BONDED TO A SOLID SUPPORT, AND METHOD FOR THEIR PREPARATION | INSTITUT PASTEUR (FR) | 1990-09-19 | — | — | EP | claimed |
| EP-0365556-A1 | NUCLEOSIDE ANALOGUES. | GENENTECH INC (US) | 1990-05-02 | — | — | EP | claimed |
| WO-1988009796-A1 | NUCLEOSIDE ANALOGUES | GENENTECH, INC. (US) | 1988-12-15 | — | — | WO | claimed |
| CN-86101792-A | The preparation method of heterogeneous ring compound | — | 1986-11-12 | — | — | CN | claimed |
| EP-0174879-A1 | Polynucleotides covalently bonded to a solid support, and method for their preparation | INSTITUT PASTEUR (FR) | 1986-03-19 | — | — | EP | claimed |
| WO-1983002891-A1 | URACIL DERIVATIVES AS ANTI-SEBORRHEIC ADDITIVES FOR COSMETIC PRODUCTS | Möller, Hinrich | 1983-09-01 | — | — | WO | claimed |