⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19376421 | 0.81 | CYP1A2 (0.57) | — | |
| SCHEMBL24350484 | 0.81 | — | — | |
| SCHEMBL10593132 | 0.81 | — | — | |
| SCHEMBL10593142 | 0.81 | — | — | |
| SCHEMBL11926 | 0.79 | — | — | |
| SCHEMBL60463 | 0.79 | — | — | |
| SCHEMBL11921 | 0.79 | — | — | |
| SCHEMBL21430668 | 0.78 | ALDH1A1 (0.56) | — | |
| SCHEMBL12847833 | 0.78 | CYP1A2 (0.50) | — | |
| Bromide SCHEMBL28177608 | 0.78 | CYP1A2 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747203-A4 | SCALABLE SYNTHESIS OF IMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2009-04-22 | — | — | EP | claimed |
| US-7507756-B2 | Scalable synthesis of imidazole derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-03-24 | — | — | US | claimed |
| EP-1747203-A1 | SCALABLE SYNTHESIS OF IMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-01-31 | — | — | EP | claimed |
| WO-2005110998-A1 | SCALABLE SYNTHESIS OF IMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-11-24 | — | — | WO | claimed |
| US-20050250948-A1 | Scalable synthesis of imidazole derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-11-10 | — | — | US | claimed |
| US-20240366518-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | LIFE EDIT THERAPEUTICS, INC. | 2024-11-07 | — | — | US | disclosed |
| CN-118324715-A | Compounds, compositions, and methods of use thereof | 艾勒维生技公司 | 2024-07-12 | — | — | CN | disclosed |
| US-20240173267-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | ONCORUS, INC. (US) | 2024-05-30 | — | — | US | disclosed |
| CN-117750962-A | Compounds, compositions, and methods of use thereof | 艾勒维生技公司 | 2024-03-22 | — | — | CN | disclosed |
| EP-4291201-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | Oncorus, Inc. (US) | 2023-12-20 | — | — | EP | disclosed |
| WO-2022173531-A9 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | ONCORUS, INC. (US) | 2023-03-02 | — | — | WO | disclosed |
| WO-2022173531-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | ONCORUS, INC. (US) | 2022-08-18 | — | — | WO | disclosed |
| US-20090143591-A1 | SCALABLE SYNTHESIS OF IMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2009-06-04 | — | — | US | disclosed |
| EP-1747203-A4 | SCALABLE SYNTHESIS OF IMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2009-04-22 | — | — | EP | disclosed |
| US-7507756-B2 | Scalable synthesis of imidazole derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-03-24 | — | — | US | disclosed |
| EP-1747203-A1 | SCALABLE SYNTHESIS OF IMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005110998-A1 | SCALABLE SYNTHESIS OF IMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-11-24 | — | — | WO | disclosed |
| US-20050250948-A1 | Scalable synthesis of imidazole derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-11-10 | — | — | US | disclosed |
| US-4618599-A | WATER SOLUBILITY | RHONE-POULENC SANTE (FR) | 1986-10-21 | — | — | US | disclosed |
| US-4617377-A | BACTERICIDES | RHONE-POULENC SANTE (FR) | 1986-10-14 | — | — | US | disclosed |