⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3131489 | 1.00 | — | — | |
| SCHEMBL41218 | 0.78 | — | — | |
| SCHEMBL102759 | 0.78 | — | — | |
| SCHEMBL160149 | 0.78 | — | — | |
| SCHEMBL41219 | 0.78 | — | — | |
| SCHEMBL483199 | 0.78 | — | — | |
| SCHEMBL137154 | 0.78 | — | — | |
| SCHEMBL10632082 | 0.74 | — | — | |
| SCHEMBL10632089 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL17688741 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260130860-A1 | LIPIDS FOR DELIVERY OF THERAPEUTIC AGENTS | FLAGSHIP LABS 114, INC. (US) | 2026-05-14 | — | — | US | disclosed |
| WO-2023225621-A2 | LIPIDS FOR DELIVERY OF THERAPEUTIC AGENTS | OMEGA THERAPEUTICS, INC. (US) | 2023-11-23 | — | — | WO | disclosed |
| US-11396515-B2 | Pyran fused ring compound, preparation method therefor and use thereof | BEIJING TIENYI LUFU PHARMATECH CO. LTD. (CN) | 2022-07-26 | — | — | US | disclosed |
| US-20220048921-A1 | PYRAN FUSED RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | BEIJING TIENYI LUFU PHARMATECH CO. LTD. (CN) | 2022-02-17 | — | — | US | disclosed |
| EP-3608323-B1 | PYRAN FUSED RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | BEIJING TIENYI LUFU PHARMATECH CO LTD (CN) | 2021-11-03 | — | — | EP | disclosed |
| CN-110218213-B | Pyran fused ring compound, preparation method and application thereof | 北京天一绿甫医药科技有限公司 | 2020-09-04 | — | — | CN | disclosed |
| EP-3608323-A1 | PYRAN FUSED RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Beijing Tienyi Lufu Pharmatech Co. Ltd. (CN) | 2020-02-12 | — | — | EP | disclosed |
| US-20180009793-A1 | METHODS AND COMPOSITIONS OF SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | ANGION BIOMEDICA CORP (US) | 2018-01-11 | — | — | US | disclosed |
| US-9663471-B2 | Pyrazole derivatives as modulators of hepatocyte growth factor (scatter factor) activity | ANGION BIOMEDICA CORPORATION (US) | 2017-05-30 | — | — | US | disclosed |
| US-9193682-B2 | Synthesis of trithiocarbonates and allyl sulfides and their application into advances in covalent adaptable networks | Fenoli, Christopher R. (US) | 2015-11-24 | — | — | US | disclosed |
| US-7250437-B2 | Small molecule modulators of hepatocyte growth factor (scatter factor) activity | ANGION BIOMEDICA CORP. (US) | 2007-07-31 | — | — | US | disclosed |
| US-7250437-B2 | Small molecule modulators of hepatocyte growth factor (scatter factor) activity | ANGION BIOMEDICA CORP. (US) | 2007-07-31 | — | — | US | disclosed |
| US-7192976-B2 | 3-substituted pyrazoles; cell proliferation and angiogenesis promoters; antiapoptotosis and antifibrosis activity | ANGION BIOMEDICA CORPORATION (US) | 2007-03-20 | — | — | US | disclosed |
| US-20070015781-A1 | Certain substituted spirocyclic lactams and use thereof as pharmaceuticals | AUBERSON YVES | 2007-01-18 | — | — | US | disclosed |
| EP-1670803-A1 | CERTAIN SUBSTITUTED SPIROCYCLIC LACTAMS AND USE THEREOF AS PHARMACEUTICALS | Novartis AG (CH) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005035535-A1 | CERTAIN SUBSTITUTED SPIROCYCLIC LACTAMS AND USE THEREOF AS PHARMACEUTICALS | NOVARTIS AG (CH) | 2005-04-21 | — | — | WO | disclosed |
| US-6441177-B1 | Tertiary amines | HOFFMANN-LA ROCHE INC. | 2002-08-27 | — | — | US | disclosed |
| EP-0778264-B1 | Tertiary amines having antimycotic and cholesterol lowering activity | HOFFMANN LA ROCHE (CH) | 2001-07-11 | — | — | EP | disclosed |
| US-6034275-A | FUGICIDES; ATICHOLESTEROL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 2000-03-07 | — | — | US | disclosed |
| EP-0778264-A1 | Tertiary amines having antimycotic and cholesterol lowering activity | F. HOFFMANN-LA ROCHE AG (CH) | 1997-06-11 | — | — | EP | disclosed |