SCHEMBL353603

SCHEMBL353603

N#Cc1ccc(F)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19439637 0.86 KDM1A (0.41)
2,5-Thiophenedinitrile SCHEMBL996528 0.80
2,5-Thiophenedinitrile SCHEMBL19436420 0.73 KDM4E (0.33)
SCHEMBL13074418 0.72 PGR (0.43)
SCHEMBL2846873 0.69
SCHEMBL19439590 0.69 DAO (0.41)
SCHEMBL5957174 0.69
SCHEMBL23704234 0.68
SCHEMBL867171 0.68
SCHEMBL8791685 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200388881-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH FUNCTIONAL THIOPHENE COMPOUNDS OR DERIVATIVES OF THIOPHENE CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION 2020-12-10 US claimed
CN-119899170-A Fluorine-containing thiophene compound, preparation method thereof and electrolyte 江苏华盛锂电材料股份有限公司 2025-04-29 CN disclosed
WO-2025034858-A1 FUSED PYRIDINES FOR THE TREATMENT OF CANCER AND OTHER INDICATIONS THERAS, INC. (US) 2025-02-13 WO disclosed
US-11569530-B2 Silicon-based energy storage devices with functional thiophene compounds or derivatives of thiophene containing electrolyte additives ENEVATE CORPORATION (US) 2023-01-31 US disclosed
US-11569530-B2 Silicon-based energy storage devices with functional thiophene compounds or derivatives of thiophene containing electrolyte additives ENEVATE CORPORATION (US) 2023-01-31 US disclosed
US-20200388881-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH FUNCTIONAL THIOPHENE COMPOUNDS OR DERIVATIVES OF THIOPHENE CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION 2020-12-10 US disclosed
US-9856247-B2 4-methyl-dihydropyrimidines for the treatment and prophylaxis of Hepatitis B virus infection HOFFMANN-LA ROCHE INC. (US) 2018-01-02 US disclosed
US-20170334898-A9 NOVEL 4-METHYL-DIHYDROPYRIMIDINES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION HOFFMANN-LA ROCHE INC. (US) 2017-11-23 US disclosed
WO-2017167638-A1 NON-AQUEOUS ELECTROLYTES AND USES THEREOF SONY CORPORATION (JP) 2017-10-05 WO disclosed
EP-2200440-B1 ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS CRESTONE INC (US) 2017-07-19 EP disclosed
US-20080090834-A1 SELECTIVE AZOLE PDE10A INHIBITOR COMPOUNDS PFIZER INC 2008-04-17 US disclosed
WO-2008043533-A2 ACYL AMINOIMIDAZOLES AND ACYL AMINOTHIAZOLES BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2008-04-17 WO disclosed
WO-2008004117-A1 SELECTIVE AZOLE PDE10A INHIBITOR COMPOUNDS PFIZER PRODUCTS INC. (US) 2008-01-10 WO disclosed
US-20060166987-A1 Opioid receptor antagonists ELI LILLY AND COMPANY 2006-07-27 US disclosed
EP-1606275-A1 OPIOID RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 2005-12-21 EP disclosed
WO-2004080996-A1 OPIOID RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 2004-09-23 WO disclosed
US-6096901-A Processes and intermediates for preparing 2-fluorothiophene derivatives PFIZER INC. (US) 2000-08-01 US disclosed
US-6043379-A Processes and intermediates for preparing 2-fluorothiophene derivatives PFIZER INC. (US) 2000-03-28 US disclosed
WO-1998045282-A1 PROCESSES AND INTERMEDIATES FOR PREPARING 2-FLUOROTHIOPHENE DERIVATIVES PFIZER INC. (US) 1998-10-15 WO disclosed
EP-0501592-A1 Triheteroarylmethanes, process for their preparation, pharmaceutical compositions containing them and their use for the preparation of medicines SCHERING AKTIENGESELLSCHAFT (DE) 1992-09-02 EP disclosed