Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35567 | 1.00 | LPAR3 (0.43) | LPAR3LPAR2CA12CA1CA2 | |
| SCHEMBL35805 | 1.00 | LPAR3 (0.43) | LPAR3LPAR2CA12CA1CA2 | |
| SCHEMBL35402 | 0.98 | CA12 (0.41) | LPAR3LPAR2CA12CA1CA2 | |
| SCHEMBL2067898 | 0.93 | LPAR3 (0.43) | LPAR3LPAR2CA12CA1CA2 | |
| SCHEMBL2068087 | 0.93 | — | — | |
| SCHEMBL2067511 | 0.93 | LPAR3 (0.43) | LPAR3LPAR2CA12CA1CA2 | |
| SCHEMBL14763440 | 0.93 | LPAR3 (0.43) | LPAR3LPAR2CA12CA1CA2 | |
| SCHEMBL5735068 | 0.93 | LPAR3 (0.43) | LPAR3LPAR2CA12CA1CA2 | |
| SCHEMBL35717 | 0.91 | ALDH1A1 (0.41) | LPAR3LPAR2CA12CA1CA2 | |
| SCHEMBL2068344 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10871595-B2 | Polymers and nanogel materials and methods for making and using the same | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2020-12-22 | — | — | US | disclosed |
| US-20200049858-A1 | POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE (US) | 2020-02-13 | — | — | US | disclosed |
| US-10301465-B2 | Non-reactive, hydrophilic polymers having terminal siloxanes and methods for making and using the same | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2019-05-28 | — | — | US | disclosed |
| US-20180341044-A1 | POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE (US) | 2018-11-29 | — | — | US | disclosed |
| EP-3401342-A1 | POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME | Johnson & Johnson Vision Care, Inc. (US) | 2018-11-14 | — | — | EP | disclosed |
| EP-2566911-B1 | NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND USES OF THE SAME | JOHNSON & JOHNSON VISION CARE (US) | 2018-10-24 | — | — | EP | disclosed |
| US-10073192-B2 | Polymers and nanogel materials and methods for making and using the same | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2018-09-11 | — | — | US | disclosed |
| EP-2855544-B1 | POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE (US) | 2018-06-20 | — | — | EP | disclosed |
| US-20180044518-A1 | NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE (US) | 2018-02-15 | — | — | US | disclosed |
| US-9815979-B2 | Non-reactive, hydrophilic polymers having terminal siloxanes and methods for making and using the same | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2017-11-14 | — | — | US | disclosed |
| US-20170051145-A1 | NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE (US) | 2017-02-23 | — | — | US | disclosed |
| US-9522980-B2 | Non-reactive, hydrophilic polymers having terminal siloxanes and methods for making and using the same | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2016-12-20 | — | — | US | disclosed |
| EP-2855547-A2 | POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME | Johnson & Johnson Vision Care Inc. (US) | 2015-04-08 | — | — | EP | disclosed |
| EP-2855544-A2 | POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME | Johnson & Johnson Vision Care Inc. (US) | 2015-04-08 | — | — | EP | disclosed |
| WO-2013176886-A2 | POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-11-28 | — | — | WO | disclosed |
| WO-2013177523-A2 | POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-11-28 | — | — | WO | disclosed |
| US-20130317131-A1 | POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-11-28 | — | — | US | disclosed |
| EP-2566911-A1 | NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND USES OF THE SAME | Johnson & Johnson Vision Care, Inc. (US) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011140318-A1 | NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND USES OF THE SAME | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2011-11-10 | — | — | WO | disclosed |
| US-20110275734-A1 | NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE, INC. | 2011-11-10 | — | — | US | disclosed |