SCHEMBL353652

SCHEMBL353652

CC(C)(C)OC(=O)NC[C@H]1CC[C@H](C(=O)O)CC1

nearest known ligand 0.71

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.71
SMN1; SMN2 Q16637 1/20 0.57
ACACB O00763 8/20 0.48
ACACA Q13085 4/20 0.48
DRD2 P14416 2/20 0.48
BTK Q06187 1/20 0.48
ATM Q13315 1/20 0.44
CKS1B P61024 1/20 0.44
SKP1 P63208 1/20 0.44
SKP2 Q13309 1/20 0.44
CTSS P25774 1/20 0.44
CTSK P43235 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL353639 1.00 KMT2A (0.71) KMT2ASMN1; SMN2ACACBACACADRD2
SCHEMBL5006161 1.00 KMT2A (0.71) KMT2ASMN1; SMN2ACACBACACADRD2
SCHEMBL4653500 0.98 KMT2A (0.69) KMT2ASMN1; SMN2ACACBACACADRD2
SCHEMBL4653502 0.98 KMT2A (0.69) KMT2ASMN1; SMN2ACACBACACADRD2
SCHEMBL25036375 0.94 KMT2A (0.64) KMT2ASMN1; SMN2ACACBACACADRD2
SCHEMBL4354977 0.91 KMT2A (0.60) KMT2ASMN1; SMN2ACACBACACADRD2
SCHEMBL4346477 0.91 KMT2A (0.60) KMT2ASMN1; SMN2ACACBACACADRD2
SCHEMBL6641585 0.91 KMT2A (0.60) KMT2ASMN1; SMN2ACACBACACADRD2
SCHEMBL6641586 0.91 KMT2A (0.60) KMT2ASMN1; SMN2ACACBACACADRD2
Bicarbonate SCHEMBL1580718 0.90 KMT2A (0.57) KMT2ASMN1; SMN2ACACBACACADRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 475 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116655516-A Compound for prostate cancer specific fluorescent probe, preparation method and application thereof 中国医学科学院肿瘤医院深圳医院 2023-08-29 CN claimed
US-12630512-B2 Agents for differentiating stem cells and treating cancer MINERVA BIOTECHNOLOGIES CORPORATION (US) 2026-05-19 US disclosed
WO-2026098607-A1 F-18 LABELED AQUEOUS PHARMACEUTICAL COMPOSITION TARGETING LIGAND OF FIBROBLAST ACTIVATION PROTEIN, AND PREPARATION METHOD THEREFOR 天津恒瑞医药有限公司 2026-05-15 WO disclosed
EP-4711362-A1 LIGAND TARGETING FIBROBLAST ACTIVATION PROTEIN Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) 2026-03-18 EP disclosed
EP-3600451-B1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MINERVA BIOTECHNOLOGIES CORP (US) 2025-12-24 EP disclosed
US-20250320217-A1 SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINES AS PROTEIN KINASE INHIBITORS SUMITOMO PHARMA AMERICA INC (US) 2025-10-16 US disclosed
US-12404274-B2 Macrocycles as factor xia inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2025-09-02 US disclosed
US-20250206724-A1 SUBSTITUTED 3-AMINO INDAZOLE DERIVATIVES AS KINASE INHIBITORS NERVIANO MEDICAL SCIENCES S.R.L. (IT) 2025-06-26 US disclosed
US-20250129085-A1 SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINES AS PROTEIN KINASE INHIBITORS SUMITOMO PHARMA AMERICA INC (US) 2025-04-24 US disclosed
US-20250092043-A1 Kinase Inhibitors and Degraders INCYTE CORPORATION 2025-03-20 US disclosed
US-5166403-A Liquid crystals SHOWA DENKO K.K. (JP) 1992-11-24 US disclosed
US-4954512-A Anti-ulcer composition Okamoto, Shosuke (JP) 1990-09-04 US disclosed
US-4895842-A Phenylalanine derivative and proteinase inhibitor SHOSUKE OKAMOTO (JP) 1990-01-23 US disclosed
US-4873253-A Phenylalanine derivative and proteinase inhibitor Okamoto, Shosuke (JP) 1989-10-10 US disclosed
EP-0317959-A2 Anti-ulcer composition Okamoto, Shosuke (JP) 1989-05-31 EP disclosed
EP-0284632-A1 Phenylalanine derivative and proteinase inhibitor Okamoto, Shosuke (JP) 1988-10-05 EP disclosed
EP-0217286-A1 Phenylalanine derivative and proteinase inhibitor Okamoto, Shosuke (JP) 1987-04-08 EP disclosed
EP-0079872-B1 ANTIFIBRINOLYTICALLY ACTIVE COMPOUNDS KabiVitrum AB (SE) 1985-03-20 EP disclosed
US-4483867-A ANTIULCER AGENTS, ANTIEDEMIC AGENTS KABIVITRUM AB (SE) 1984-11-20 US disclosed
EP-0079872-A1 Antifibrinolytically active compounds KabiVitrum AB (SE) 1983-05-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12404274-B2 Macrocycles as factor xia inhibitors TFPI, TFPI2, F11 KMT2A 1111/4885SMN1; SMN2 3689/4885ACACB 3205/4885
US-20250206724-A1 SUBSTITUTED 3-AMINO INDAZOLE DERIVATIVES AS KINASE INHIBITORS CDK1, CDK11A, CDK3 KMT2A 1352/4885SMN1; SMN2 2939/4885ACACB 1678/4885
US-20250129085-A1 SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINES AS PROTEIN KINASE INHIBITORS PIM1, PIM2, PIM3 KMT2A 1046/4885SMN1; SMN2 3075/4885ACACB 4426/4885
US-12630512-B2 Agents for differentiating stem cells and treating cancer MCL1, POU2F1, NES KMT2A 1674/4885SMN1; SMN2 646/4885ACACB 1455/4885
US-20250320217-A1 SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINES AS PROTEIN KINASE INHIBITORS PIM1, PIM2, PIM3 KMT2A 1046/4885SMN1; SMN2 3075/4885ACACB 4426/4885
US-20250092043-A1 Kinase Inhibitors and Degraders JAK2, JAK1, JAK3 KMT2A 339/4885SMN1; SMN2 3432/4885ACACB 3066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.