Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 15/20 | 0.62 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2567265 | 0.88 | CCR3 (0.56) | CCR3MAPK8 | |
| SCHEMBL2565277 | 0.83 | CCR3 (0.61) | CCR3 | |
| SCHEMBL2564463 | 0.77 | CCR3 (1.00) | CCR3 | |
| SCHEMBL1098034 | 0.73 | CCR3 (1.00) | CCR3 | |
| SCHEMBL1107155 | 0.72 | CCR3 (0.78) | CCR3 | |
| SCHEMBL2564429 | 0.72 | CCR3 (0.59) | CCR3 | |
| SCHEMBL2565773 | 0.69 | CCR3 (1.00) | CCR3 | |
| SCHEMBL6810820 | 0.68 | IDO1 (0.45) | RBP4 | |
| SCHEMBL10395443 | 0.66 | KHK (0.46) | RBP4 | |
| SCHEMBL22773231 | 0.65 | CNR1 (0.44) | RBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759365-B2 | Piperidine-substituted indoles | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-07-20 | — | — | US | disclosed |
| US-20060247230-A1 | Novel Piperidine-Substituted Indoles | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247230-A1 | Novel Piperidine-Substituted Indoles | CCR3, CCR1, CCR2 | CCR3 1/4885RBP4 3346/4885MAPK8 3219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.