Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 2/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17743460 | 1.00 | KDM4E (0.52) | KDM4ESMN1; SMN2HTTALDH1A1CYP1A2 | |
| SCHEMBL17743410 | 1.00 | KDM4E (0.52) | KDM4ESMN1; SMN2HTTALDH1A1CYP1A2 | |
| SCHEMBL17743423 | 0.98 | KDM4E (0.48) | KDM4ESMN1; SMN2HTTALDH1A1CYP1A2 | |
| SCHEMBL17743425 | 0.94 | KDM4E (0.43) | KDM4ESMN1; SMN2HTTALDH1A1CYP1A2 | |
| SCHEMBL4299479 | 0.89 | — | — | |
| SCHEMBL19148980 | 0.88 | KDM4E (0.48) | KDM4ESMN1; SMN2HTTALDH1A1CYP1A2 | |
| SCHEMBL7777018 | 0.83 | ALDH1A1 (0.52) | KDM4ESMN1; SMN2HTTALDH1A1CYP1A2 | |
| SCHEMBL3679901 | 0.83 | ALDH1A1 (0.52) | KDM4ESMN1; SMN2HTTALDH1A1CYP1A2 | |
| SCHEMBL7776906 | 0.80 | ALDH1A1 (0.53) | KDM4ESMN1; SMN2HTTALDH1A1CYP1A2 | |
| SCHEMBL10895092 | 0.79 | KDM4E (0.42) | KDM4ESMN1; SMN2ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3020464-B1 | ACIDIC GAS ABSORBING AGENT, METHOD FOR REMOVING ACIDIC GAS AND APPARATUS FOR REMOVING ACIDIC GAS | TOSHIBA KK (JP) | 2019-10-02 | — | — | EP | claimed |
| CN-112079732-B | Synthetic route of 4-alkyl secondary amino-2-butanol compound | 湖南大学 | 2021-10-08 | — | — | CN | disclosed |
| CN-112079732-A | Synthetic route of 4-alkyl secondary amino-2-butanol compound | 湖南大学 | 2020-12-15 | — | — | CN | disclosed |
| EP-3020464-B1 | ACIDIC GAS ABSORBING AGENT, METHOD FOR REMOVING ACIDIC GAS AND APPARATUS FOR REMOVING ACIDIC GAS | TOSHIBA KK (JP) | 2019-10-02 | — | — | EP | disclosed |
| CN-105597492-B | The removing method and sour gas removing device of acid gas absorbent, sour gas | 株式会社东芝 | 2018-11-16 | — | — | CN | disclosed |
| US-9446346-B2 | Acidic gas absorbing agent, method for removing acidic gas and apparatus for removing acidic gas | KABUSHIKI KAISHA TOSHIBA (JP) | 2016-09-20 | — | — | US | disclosed |
| CN-105597492-A | Acidic gas absorbing agent, method for removing acidic gas and apparatus for removing acidic gas | TOSHIBA KK | 2016-05-25 | — | — | CN | disclosed |
| US-20160136568-A1 | ACIDIC GAS ABSORBING AGENT, METHOD FOR REMOVING ACIDIC GAS AND APPARATUS FOR REMOVING ACIDIC GAS | KABUSHIKI KAISHA TOSHIBA (JP) | 2016-05-19 | — | — | US | disclosed |
| EP-3020464-A1 | ACIDIC GAS ABSORBING AGENT, METHOD FOR REMOVING ACIDIC GAS AND APPARATUS FOR REMOVING ACIDIC GAS | Kabushiki Kaisha Toshiba (JP) | 2016-05-18 | — | — | EP | disclosed |
| US-7687507-B2 | Pyrrolo[2,3-d]pyrimidine compounds | PFIZER INC. (US) | 2010-03-30 | — | — | US | disclosed |
| US-20050171128-A1 | Pyrrolo[2,3-d]pyrimidine compounds | PFIZER INC | 2005-08-04 | — | — | US | disclosed |
| US-6890929-B2 | Immunosuppressants; lupus, multiple sclerosis, skin disorders, antiarthritic agents, antihistamines, antiulcer agents, Crohn's disease | PFIZER, INC. (US) | 2005-05-10 | — | — | US | disclosed |
| EP-1087970-B1 | PYRROLO 2,3-d]PYRIMIDINE COMPOUNDS | PFIZER PROD INC (US) | 2004-04-28 | — | — | EP | disclosed |
| US-20030212273-A1 | Pyrrolo [2,3-D] pyrimidine compounds | PFIZER INC. | 2003-11-13 | — | — | US | disclosed |
| US-6610847-B2 | Tyrosine kinase inhibitors; immunosuppressants | PFIZER INC. | 2003-08-26 | — | — | US | disclosed |
| US-20020019526-A1 | Pyrrolo[2,3-d]pyrimidine compounds | PFIZER INC. | 2002-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019526-A1 | Pyrrolo[2,3-d]pyrimidine compounds | JAK1, JAK3, JAK2 | KDM4E 1999/4885SMN1; SMN2 3484/4885HTT 4247/4885 |
| US-20050171128-A1 | Pyrrolo[2,3-d]pyrimidine compounds | JAK3, JAK1, JAK2 | KDM4E 1567/4885SMN1; SMN2 3594/4885HTT 4169/4885 |
| US-20030212273-A1 | Pyrrolo [2,3-D] pyrimidine compounds | JAK1, JAK3, JAK2 | KDM4E 1999/4885SMN1; SMN2 3484/4885HTT 4247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.